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Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study

Most Mycobacterium tuberculosis (Mtb) resistant to rifampicin (RIF) has mutations in the rpoB gene, while most Mtb resistant to isoniazid (INH) has mutations in the katG gene or inhA promoter. We used gene chip technology to detect mutations in these genes to determine the resistance of Mtb to RIF a...

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Detalles Bibliográficos
Autores principales: Feng, Gang, Han, Wenhao, Shi, Jinyan, Xia, Rongrong, Xu, Jianchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429459/
https://www.ncbi.nlm.nih.gov/pubmed/34504243
http://dx.doi.org/10.1038/s41598-021-97559-y