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Inhibition of CCL2 by bindarit alleviates diabetes-associated periodontitis by suppressing inflammatory monocyte infiltration and altering macrophage properties
Diabetes-associated periodontitis (DP) aggravates diabetic complications and increases mortality from diabetes. DP is caused by diabetes-enhanced host immune-inflammatory responses to bacterial insult. In this study, we found that persistently elevated CCL2 levels in combination with proinflammatory...
Autores principales: | Shen, Zongshan, Kuang, Shuhong, Zhang, Min, Huang, Xin, Chen, Jiayao, Guan, Meiliang, Qin, Wei, Xu, Hockin H. K., Lin, Zhengmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429574/ https://www.ncbi.nlm.nih.gov/pubmed/32678310 http://dx.doi.org/10.1038/s41423-020-0500-1 |
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