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Covalent linkage of sulfated hyaluronan to the collagen scaffold Mucograft® enhances scaffold stability and reduces proinflammatory macrophage activation in vivo

Sulfated glycosaminoglycans (sGAG) show interaction with biological mediator proteins. Although collagen-based biomaterials are widely used in clinics, their combination with high-sulfated hyaluronan (sHA3) is unexplored. This study aims to functionalize a collagen-based scaffold (Mucograft®) with s...

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Detalles Bibliográficos
Autores principales:	Al-Maawi, Sarah, Rother, Sandra, Halfter, Norbert, Fiebig, Karen M., Moritz, Juliane, Moeller, Stephanie, Schnabelrauch, Matthias, Kirkpatrick, Charles James, Sader, Robert, Wiesmann, Hans-Peter, Scharnweber, Dieter, Hintze, Vera, Ghanaati, Shahram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	KeAi Publishing 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429620/ https://www.ncbi.nlm.nih.gov/pubmed/34541411 http://dx.doi.org/10.1016/j.bioactmat.2021.06.008

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