Capturing the perfect pose

Lipid nanoparticles can be used to deliver nucleic acids for gene expression modulation—but getting them to target specific tissues is an ongoing challenge. In a new study by Dammes et al., a conformation-sensitive targeting strategy is used to achieve better selectivity in silencing gut-homing leuk...

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Detalles Bibliográficos
Autor principal: Akhtar, Anam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429666/
https://www.ncbi.nlm.nih.gov/pubmed/34504279
http://dx.doi.org/10.1038/s42003-021-02591-3
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author Akhtar, Anam
author_facet Akhtar, Anam
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description Lipid nanoparticles can be used to deliver nucleic acids for gene expression modulation—but getting them to target specific tissues is an ongoing challenge. In a new study by Dammes et al., a conformation-sensitive targeting strategy is used to achieve better selectivity in silencing gut-homing leukocytes in mouse models of colitis.
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spelling pubmed-84296662021-09-24 Capturing the perfect pose Akhtar, Anam Commun Biol Research Highlight Lipid nanoparticles can be used to deliver nucleic acids for gene expression modulation—but getting them to target specific tissues is an ongoing challenge. In a new study by Dammes et al., a conformation-sensitive targeting strategy is used to achieve better selectivity in silencing gut-homing leukocytes in mouse models of colitis. Nature Publishing Group UK 2021-09-09 /pmc/articles/PMC8429666/ /pubmed/34504279 http://dx.doi.org/10.1038/s42003-021-02591-3 Text en © Springer Nature Limited 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Highlight
Akhtar, Anam
Capturing the perfect pose
title Capturing the perfect pose
title_full Capturing the perfect pose
title_fullStr Capturing the perfect pose
title_full_unstemmed Capturing the perfect pose
title_short Capturing the perfect pose
title_sort capturing the perfect pose
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429666/
https://www.ncbi.nlm.nih.gov/pubmed/34504279
http://dx.doi.org/10.1038/s42003-021-02591-3
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