CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data

Systematic DNA sequencing of cancer samples has highlighted the importance of two aspects of cancer genomics: intra-tumor heterogeneity (ITH) and mutational processes. These two aspects may not always be independent, as different mutational processes could be involved in different stages or regions...

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Detalles Bibliográficos
Autores principales: Abécassis, Judith, Reyal, Fabien, Vert, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429716/
https://www.ncbi.nlm.nih.gov/pubmed/34504064
http://dx.doi.org/10.1038/s41467-021-24992-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429716/
https://www.ncbi.nlm.nih.gov/pubmed/34504064
http://dx.doi.org/10.1038/s41467-021-24992-y

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