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Effect of metformin treatment and its time of administration on joint capsular fibrosis induced by mouse knee immobilization

Joint contracture leads to major patient discomfort. Metformin, one of the most extensively used oral drugs against type 2 diabetes has recently been found to suppress tissue fibrosis as well. However, its role in suppressing tissue fibrosis in joint contractures remains unknown. In this study, we e...

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Detalles Bibliográficos
Autores principales:	Tokuda, Kotaro, Yamanaka, Yoshiaki, Mano, Yosuke, Tsukamoto, Manabu, Tajima, Takafumi, Suzuki, Hitoshi, Kawasaki, Makoto, Uchida, Soshi, Nakamura, Eiichiro, Wang, Ke-Yong, Sakai, Akinori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429753/ https://www.ncbi.nlm.nih.gov/pubmed/34504209 http://dx.doi.org/10.1038/s41598-021-97445-7

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