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Right ventricular myocardial oxygen tension is reduced in monocrotaline-induced pulmonary hypertension in the rat and restored by myo-inositol trispyrophosphate

Pulmonary hypertension (PH) initially results in compensatory right ventricular (RV) hypertrophy, but eventually in RV failure. This transition is poorly understood, but may be triggered by hypoxia. Measurements of RV oxygen tension (pO(2)) in PH are lacking. We hypothesized that RV hypoxia occurs i...

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Detalles Bibliográficos
Autores principales: Oknińska, Marta, Zambrowska, Zuzanna, Zajda, Karolina, Paterek, Aleksandra, Brodaczewska, Klaudia, Mackiewicz, Urszula, Szczylik, Cezary, Torbicki, Adam, Kieda, Claudine, Mączewski, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429755/
https://www.ncbi.nlm.nih.gov/pubmed/34504231
http://dx.doi.org/10.1038/s41598-021-97470-6

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