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Regulation of Extracellular Matrix Production in Activated Fibroblasts: Roles of Amino Acid Metabolism in Collagen Synthesis

Cancer associated fibroblasts (CAFs) are a major component of the tumour microenvironment in most tumours, and are key mediators of the response to tissue damage caused by tumour growth and invasion, contributing to the observation that tumours behave as ‘wounds that do not heal’. CAFs have been sho...

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Detalles Bibliográficos
Autores principales: Kay, Emily J., Koulouras, Grigorios, Zanivan, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429785/
https://www.ncbi.nlm.nih.gov/pubmed/34513697
http://dx.doi.org/10.3389/fonc.2021.719922