Cargando…
Regulation of Extracellular Matrix Production in Activated Fibroblasts: Roles of Amino Acid Metabolism in Collagen Synthesis
Cancer associated fibroblasts (CAFs) are a major component of the tumour microenvironment in most tumours, and are key mediators of the response to tissue damage caused by tumour growth and invasion, contributing to the observation that tumours behave as ‘wounds that do not heal’. CAFs have been sho...
Autores principales: | Kay, Emily J., Koulouras, Grigorios, Zanivan, Sara |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429785/ https://www.ncbi.nlm.nih.gov/pubmed/34513697 http://dx.doi.org/10.3389/fonc.2021.719922 |
Ejemplares similares
-
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
por: Kay, Emily J., et al.
Publicado: (2022) -
Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
por: Kay, Emily J., et al.
Publicado: (2022) -
Targeting collagen in tumor extracellular matrix as a novel targeted strategy in cancer immunotherapy
por: Liu, Jiayang, et al.
Publicado: (2023) -
3D Extracellular Matrix Regulates the Activity of T Cells and Cancer Associated Fibroblasts in Breast Cancer
por: Gao, Huan, et al.
Publicado: (2021) -
Upregulated Collagen COL10A1 Remodels the Extracellular Matrix and Promotes Malignant Progression in Lung Adenocarcinoma
por: Liang, Yingkuan, et al.
Publicado: (2020)