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Valproic Acid Regulates HR and Cell Cycle Through MUS81-pRPA2 Pathway in Response to Hydroxyurea

Breast cancer is the primary problem threatening women’s health. The combined application of valproic acid (VPA) and hydroxyurea (HU) has a synergistic effect on killing breast cancer cells, but the molecular mechanism remains elusive. Replication protein A2 phosphorylation (pRPA2), is essential for...

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Detalles Bibliográficos
Autores principales:	Su, Benyu, Lim, David, Tian, Zhujun, Liu, Guochao, Ding, Chenxia, Cai, Zuchao, Chen, Chen, Zhang, Fengmei, Feng, Zhihui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429838/ https://www.ncbi.nlm.nih.gov/pubmed/34513672 http://dx.doi.org/10.3389/fonc.2021.681278

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