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Machine learning techniques to predict different levels of hospital care of CoVid-19

In this study, we analyze the capability of several state of the art machine learning methods to predict whether patients diagnosed with CoVid-19 (CoronaVirus disease 2019) will need different levels of hospital care assistance (regular hospital admission or intensive care unit admission), during th...

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Autores principales: Hernández-Pereira, Elena, Fontenla-Romero, Oscar, Bolón-Canedo, Verónica, Cancela-Barizo, Brais, Guijarro-Berdiñas, Bertha, Alonso-Betanzos, Amparo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429889/
https://www.ncbi.nlm.nih.gov/pubmed/34764619
http://dx.doi.org/10.1007/s10489-021-02743-2
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author Hernández-Pereira, Elena
Fontenla-Romero, Oscar
Bolón-Canedo, Verónica
Cancela-Barizo, Brais
Guijarro-Berdiñas, Bertha
Alonso-Betanzos, Amparo
author_facet Hernández-Pereira, Elena
Fontenla-Romero, Oscar
Bolón-Canedo, Verónica
Cancela-Barizo, Brais
Guijarro-Berdiñas, Bertha
Alonso-Betanzos, Amparo
author_sort Hernández-Pereira, Elena
collection PubMed
description In this study, we analyze the capability of several state of the art machine learning methods to predict whether patients diagnosed with CoVid-19 (CoronaVirus disease 2019) will need different levels of hospital care assistance (regular hospital admission or intensive care unit admission), during the course of their illness, using only demographic and clinical data. For this research, a data set of 10,454 patients from 14 hospitals in Galicia (Spain) was used. Each patient is characterized by 833 variables, two of which are age and gender and the other are records of diseases or conditions in their medical history. In addition, for each patient, his/her history of hospital or intensive care unit (ICU) admissions due to CoVid-19 is available. This clinical history will serve to label each patient and thus being able to assess the predictions of the model. Our aim is to identify which model delivers the best accuracies for both hospital and ICU admissions only using demographic variables and some structured clinical data, as well as identifying which of those are more relevant in both cases. The results obtained in the experimental study show that the best models are those based on oversampling as a preprocessing phase to balance the distribution of classes. Using these models and all the available features, we achieved an area under the curve (AUC) of 76.1% and 80.4% for predicting the need of hospital and ICU admissions, respectively. Furthermore, feature selection and oversampling techniques were applied and it has been experimentally verified that the relevant variables for the classification are age and gender, since only using these two features the performance of the models is not degraded for the two mentioned prediction problems.
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spelling pubmed-84298892021-09-10 Machine learning techniques to predict different levels of hospital care of CoVid-19 Hernández-Pereira, Elena Fontenla-Romero, Oscar Bolón-Canedo, Verónica Cancela-Barizo, Brais Guijarro-Berdiñas, Bertha Alonso-Betanzos, Amparo Appl Intell (Dordr) Article In this study, we analyze the capability of several state of the art machine learning methods to predict whether patients diagnosed with CoVid-19 (CoronaVirus disease 2019) will need different levels of hospital care assistance (regular hospital admission or intensive care unit admission), during the course of their illness, using only demographic and clinical data. For this research, a data set of 10,454 patients from 14 hospitals in Galicia (Spain) was used. Each patient is characterized by 833 variables, two of which are age and gender and the other are records of diseases or conditions in their medical history. In addition, for each patient, his/her history of hospital or intensive care unit (ICU) admissions due to CoVid-19 is available. This clinical history will serve to label each patient and thus being able to assess the predictions of the model. Our aim is to identify which model delivers the best accuracies for both hospital and ICU admissions only using demographic variables and some structured clinical data, as well as identifying which of those are more relevant in both cases. The results obtained in the experimental study show that the best models are those based on oversampling as a preprocessing phase to balance the distribution of classes. Using these models and all the available features, we achieved an area under the curve (AUC) of 76.1% and 80.4% for predicting the need of hospital and ICU admissions, respectively. Furthermore, feature selection and oversampling techniques were applied and it has been experimentally verified that the relevant variables for the classification are age and gender, since only using these two features the performance of the models is not degraded for the two mentioned prediction problems. Springer US 2021-09-10 2022 /pmc/articles/PMC8429889/ /pubmed/34764619 http://dx.doi.org/10.1007/s10489-021-02743-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Hernández-Pereira, Elena
Fontenla-Romero, Oscar
Bolón-Canedo, Verónica
Cancela-Barizo, Brais
Guijarro-Berdiñas, Bertha
Alonso-Betanzos, Amparo
Machine learning techniques to predict different levels of hospital care of CoVid-19
title Machine learning techniques to predict different levels of hospital care of CoVid-19
title_full Machine learning techniques to predict different levels of hospital care of CoVid-19
title_fullStr Machine learning techniques to predict different levels of hospital care of CoVid-19
title_full_unstemmed Machine learning techniques to predict different levels of hospital care of CoVid-19
title_short Machine learning techniques to predict different levels of hospital care of CoVid-19
title_sort machine learning techniques to predict different levels of hospital care of covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429889/
https://www.ncbi.nlm.nih.gov/pubmed/34764619
http://dx.doi.org/10.1007/s10489-021-02743-2
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