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Time effect of rutaecarpine on caffeine pharmacokinetics in rats

Rutaecarpine is reported as a potent inducer of CYP1A2 enzyme in rats. There are natural herbal supplements containing rutaecarpine that are designed to enhance the CYP1A2-dependent removal of caffeine from blood so that people can have coffee later in the day without causing sleep interference. Thi...

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Detalles Bibliográficos
Autores principales: Estari, Rohit Kumar, Dong, Jin, Chan, William K., Park, Miki Susanto, Zhou, Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429912/
https://www.ncbi.nlm.nih.gov/pubmed/34527815
http://dx.doi.org/10.1016/j.bbrep.2021.101121

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