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Dynamics and epigenetic signature of regulatory T-cells following antiretroviral therapy initiation in acute HIV infection

BACKGROUND: HIV infection promotes the expansion of immunosuppressive regulatory T-cells (Tregs), contributing to immune dysfunction, tissue fibrosis and disease progression. Early antiretroviral treatment (ART) upon HIV infection improves CD4 count and decreases immune activation. However, Treg dyn...

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Detalles Bibliográficos
Autores principales:	Yero, Alexis, Shi, Tao, Farnos, Omar, Routy, Jean-Pierre, Tremblay, Cécile, Durand, Madeleine, Tsoukas, Christos, Costiniuk, Cecilia T., Jenabian, Mohammad-Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429924/ https://www.ncbi.nlm.nih.gov/pubmed/34500304 http://dx.doi.org/10.1016/j.ebiom.2021.103570

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