Cargando…

PSC-MSC-Derived Exosomes Protect against Kidney Fibrosis In Vivo and In Vitro through the SIRT6/β-Catenin Signaling Pathway

BACKGROUND AND OBJECTIVES: Chronic kidney disease (CKD) has a major impact on the quality of life of patients, and renal fibrosis is a critical pathological change in the disease. It is very important to control the process of renal fibrosis to improve the quality of life of patients with CKD. The p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Limin, Wu, Yao, Wang, Pingan, Shi, Min, Wang, Juning, Ma, Huaifen, Sun, Dangze
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Stem Cell Research 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429948/ https://www.ncbi.nlm.nih.gov/pubmed/34158415 http://dx.doi.org/10.15283/ijsc20184

Ejemplares similares

Galectin-3 Derived from HucMSC Exosomes Promoted Myocardial Fibroblast-to-Myofibroblast Differentiation Associated with β-catenin Upregulation
por: Guo, Qinyu, et al.
Publicado: (2021)

Editorial: MSC-derived exosomes in tissue regeneration
por: Chen, Xin-Ming, et al.
Publicado: (2023)

Huc-MSC-derived exosomes modified with the targeting peptide of aHSCs for liver fibrosis therapy
por: Lin, Yan, et al.
Publicado: (2022)

Corrigendum: Editorial: MSC-derived exosomes in tissue regeneration
por: Chen, Xin-Ming, et al.
Publicado: (2023)

hMSC exosomes as a novel treatment for female sensitive skin: An in vivo study
por: Ye, Congxiu, et al.
Publicado: (2022)

BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling
por: Zuo, Rui, et al.
Publicado: (2019)

Wnt/β-catenin signaling and kidney fibrosis
por: Tan, Roderick J, et al.
Publicado: (2014)

Bioengineered MSC-derived exosomes in skin wound repair and regeneration
por: Zhao, Hanxing, et al.
Publicado: (2023)

Correction to: BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling
por: Zuo, Rui, et al.
Publicado: (2020)

hucMSC-derived exosomes protect ovarian reserve and restore ovarian function in cisplatin treated mice
por: Xiao, Yue, et al.
Publicado: (2023)

Macrophages Modulate the Function of MSC- and iPSC-Derived Fibroblasts in the Presence of Polyethylene Particles
por: Gao, Qi, et al.
Publicado: (2021)

Dual Role of MSC-Derived Exosomes in Tumor Development
por: Zhao, Rou, et al.
Publicado: (2020)

Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
por: Kore, Rajshekhar A., et al.
Publicado: (2019)

Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes
por: Loh, Jia Tong, et al.
Publicado: (2022)

Editorial: In Search of In vivo MSC
por: Pacini, Simone, et al.
Publicado: (2017)

Exosomes derived from hucMSC attenuate renal fibrosis through CK1δ/β-TRCP-mediated YAP degradation
por: Ji, Cheng, et al.
Publicado: (2020)

SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro
por: Zhou, Yuanfei, et al.
Publicado: (2016)

Pre-Conditioning with IFN-γ and Hypoxia Enhances the Angiogenic Potential of iPSC-Derived MSC Secretome
por: Wang, Suya, et al.
Publicado: (2022)

HucMSC exosome-delivered 14-3-3ζ alleviates ultraviolet radiation-induced photodamage via SIRT1 pathway modulation
por: Wu, Peipei, et al.
Publicado: (2021)

Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials
por: Lotfy, Ahmed, et al.
Publicado: (2023)

Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome
por: Lai, Ruenn Chai, et al.
Publicado: (2012)

Potential Effects of MSC-Derived Exosomes in Neuroplasticity in Alzheimer’s Disease
por: Reza-Zaldivar, Edwin E., et al.
Publicado: (2018)

The Unique Immunomodulatory Properties of MSC-Derived Exosomes in Organ Transplantation
por: Zheng, Qingyuan, et al.
Publicado: (2021)

Ameliorative role of SIRT1 in peritoneal fibrosis: an in vivo and in vitro study
por: Guo, Yanhong, et al.
Publicado: (2021)

Low-Intensity Pulsed Ultrasound Promotes Osteogenic Potential of iPSC-Derived MSCs but Fails to Simplify the iPSC-EB-MSC Differentiation Process
por: Hua, Ziyi, et al.
Publicado: (2022)

Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis
por: Zhang, Jie Ting, et al.
Publicado: (2017)

The microRNA regulatory landscape of MSC-derived exosomes: a systems view
por: Ferguson, Scott W., et al.
Publicado: (2018)

MSC exosome works through a protein-based mechanism of action
por: Toh, Wei Seong, et al.
Publicado: (2018)

Defined MSC exosome with high yield and purity to improve regenerative activity
por: Kim, Jun Yong, et al.
Publicado: (2021)

Author Correction: Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
por: Kore, Rajshekhar A., et al.
Publicado: (2022)

Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy
por: Wang, Bingying, et al.
Publicado: (2017)

Combining MSC Exosomes and Cerium Oxide Nanocrystals for Enhanced Dry Eye Syndrome Therapy
por: Tian, Ying, et al.
Publicado: (2023)

MSC-Derived Exosome Promotes M2 Polarization and Enhances Cutaneous Wound Healing
por: He, Xiaoning, et al.
Publicado: (2019)

Curcumin protects against myocardial infarction-induced cardiac fibrosis via SIRT1 activation in vivo and in vitro
por: Xiao, Jie, et al.
Publicado: (2016)

Acute myeloid leukemia cells and MSC-derived exosomes inhibiting transformation in myelodysplastic syndrome
por: Liu, Xiaoli, et al.
Publicado: (2023)

Melatonin contributes to the hypertrophic differentiation of mesenchymal stem cell-derived chondrocytes via activation of the Wnt/β-catenin signaling pathway: Melatonin promotes MSC-derived chondrocytes hypertrophy
por: Wang, Xuan, et al.
Publicado: (2021)

PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
por: Wang, Yuan, et al.
Publicado: (2022)

Therapeutic MSC exosomes are derived from lipid raft microdomains in the plasma membrane
por: Tan, Soon Sim, et al.
Publicado: (2013)

Intracellular acting tumor cell-targeted chemotherapy by MSC-suicide gene exosomes
por: Altaner, Cestmir, et al.
Publicado: (2019)

Human MSC-Derived Exosomes Reduce Cellular Senescence in Renal Epithelial Cells
por: Liao, Chieh Ming, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_19g3on01i05b8drnfke8njrr65