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The deubiquitinase USP10 restores PTEN activity and inhibits non–small cell lung cancer cell proliferation

The phosphatase and tensin homolog deleted on chromosome 10 (PTEN) protein is a key player in tumorigenesis of non–small cell lung cancer (NSCLC) and was recently found to be inactivated by tripartite motif containing 25 (TRIM25)–mediated K63-linked polyubiquitination. However, the deubiquitinase (D...

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Detalles Bibliográficos
Autores principales:	He, Yuanming, Jiang, Shuoyi, Mao, Chenyu, Zheng, Hui, Cao, Biyin, Zhang, Zubin, Zhao, Jun, Zeng, Yuanying, Mao, Xinliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429974/ https://www.ncbi.nlm.nih.gov/pubmed/34416231 http://dx.doi.org/10.1016/j.jbc.2021.101088

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