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Clemastine Fumarate Attenuates Myocardial Ischemia Reperfusion Injury Through Inhibition of Mast Cell Degranulation

Mast cell (MC) activation is associated with myocardial ischemia reperfusion injury (MIRI). Suppression of MC degranulation might be a target of anti-MIRI. This study aimed to determine whether clemastine fumarate (CLE) could attenuate MIRI by inhibiting MC degranulation. A rat ischemia and reperfus...

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Detalles Bibliográficos
Autores principales:	Meng, Shuqi, Sun, Xiaotong, Juan, Zhaodong, Wang, Mingling, Wang, Ruoguo, Sun, Lina, Li, Yaozu, Xin, Anran, Li, Shuping, Li, Yao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430029/ https://www.ncbi.nlm.nih.gov/pubmed/34512339 http://dx.doi.org/10.3389/fphar.2021.704852

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