Cargando…

With Chitosan and PLGA as the Delivery Vehicle, Toxoplasma gondii Oxidoreductase-Based DNA Vaccines Decrease Parasite Burdens in Mice

Toxoplasma gondii (T. gondii) is an intracellular parasitic protozoan that can cause serious public health problems. However, there is no effectively preventive or therapeutic strategy available for human and animals. In the present study, we developed a DNA vaccine encoding T. gondii oxidoreductase...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Zhengqing, Cao, Wandi, Gao, Xuchen, Aleem, Muhammad Tahir, Liu, Junlong, Luo, Jianxun, Yan, Ruofeng, Xu, Lixin, Song, Xiaokai, Li, Xiangrui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430031/ https://www.ncbi.nlm.nih.gov/pubmed/34512659 http://dx.doi.org/10.3389/fimmu.2021.726615

Ejemplares similares

Toxoplasma gondii Proteasome Subunit Alpha Type 1 with Chitosan: A Promising Alternative to Traditional Adjuvant
por: Yu, Zhengqing, et al.
Publicado: (2021)

Nano DNA Vaccine Encoding Toxoplasma gondii Histone Deacetylase SIR2 Enhanced Protective Immunity in Mice
por: Yu, Zhengqing, et al.
Publicado: (2021)

Recombinant Toxoplasma gondii Ribosomal Protein P2 Modulates the Functions of Murine Macrophages In Vitro and Provides Immunity against Acute Toxoplasmosis In Vivo
por: Yu, Zhengqing, et al.
Publicado: (2021)

Modulation Effects of Toxoplasma gondii Histone H2A1 on Murine Macrophages and Encapsulation with Polymer as a Vaccine Candidate
por: Yu, Zhengqing, et al.
Publicado: (2020)

Nano vaccines for T. gondii Ribosomal P2 Protein With Nanomaterials as a Promising DNA Vaccine Against Toxoplasmosis
por: Yu, ZhengQing, et al.
Publicado: (2022)

PLGA Nanospheres as Delivery Platforms for Eimeria mitis 1a Protein: A Novel Strategy to Improve Specific Immunity
por: Xu, Lixin, et al.
Publicado: (2022)

Toxoplasma gondii Elongation Factor 1-Alpha (TgEF-1α) Is a Novel Vaccine Candidate Antigen against Toxoplasmosis
por: Wang, Shuai, et al.
Publicado: (2017)

Divergent features of the coenzyme Q:cytochrome c oxidoreductase complex in Toxoplasma gondii parasites
por: Hayward, Jenni A., et al.
Publicado: (2021)

Toxoplasma gondii Histone 4 Affects Some Functions of Murine Ana‐1 Macrophages In Vitro
por: Liu, Xinchao, et al.
Publicado: (2018)

Effects of Recombinant Toxoplasma gondii Citrate Synthase I on the Cellular Functions of Murine Macrophages In vitro
por: Liu, Xinchao, et al.
Publicado: (2017)

DNA vaccination with a gene encoding Toxoplasma gondii Deoxyribose Phosphate Aldolase (TgDPA) induces partial protective immunity against lethal challenge in mice
por: Hassan, Ibrahim A, et al.
Publicado: (2014)

Inhibition of Trichinella spiralis Membrane-Associated Progesterone Receptor (MAPR) Results in a Reduction in Worm Burden
por: Aleem, Muhammad Tahir, et al.
Publicado: (2023)

Prenyl Transferases Regulate Secretory Protein Sorting and Parasite Morphology in Toxoplasma gondii
por: Wang, Qiang-Qiang, et al.
Publicado: (2023)

Proteomics analysis reveals that the proto-oncogene eIF-5A indirectly influences the growth, invasion and replication of Toxoplasma gondii tachyzoite
por: Liu, Xinchao, et al.
Publicado: (2021)

Toxoplasma gondii excretory/secretory antigens (TgESAs) suppress pro-inflammatory cytokine secretion by inhibiting TLR-induced NF-κB activation in LPS-stimulated murine macrophages
por: Wang, Shuai, et al.
Publicado: (2017)

Biochemical Studies of Mitochondrial Malate: Quinone Oxidoreductase from Toxoplasma gondii
por: Acharjee, Rajib, et al.
Publicado: (2021)

Excretory/secretory proteins inhibit host immune responses by downregulating the TLR4/NF-κB/MAPKs signaling pathway: A possible mechanism of immune evasion in parasitic nematode Haemonchus contortus
por: Wen, Zhaohai, et al.
Publicado: (2022)

Nanoparticles (PLGA and Chitosan)-Entrapped ADP-Ribosylation Factor 1 of Haemonchus contortus Enhances the Immune Responses in ICR Mice
por: Hasan, Muhammad Waqqas, et al.
Publicado: (2020)

A multiepitope vaccine encoding four Eimeria epitopes with PLGA nanospheres: a novel vaccine candidate against coccidiosis in laying chickens
por: Yu, ZhengQing, et al.
Publicado: (2022)

Protective immunity against acute toxoplasmosis in BALB/c mice induced by a DNA vaccine encoding Toxoplasma gondii elongation factor 1-alpha
por: Wang, Shuai, et al.
Publicado: (2015)

Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in Toxoplasma gondii
por: Xia, Ningbo, et al.
Publicado: (2019)

Molecular Docking and In Silico Simulation of Trichinella spiralis Membrane-Associated Progesterone Receptor Component 2 (Ts-MAPRC2) and Its Interaction with Human PGRMC1
por: Aleem, Muhammad Tahir, et al.
Publicado: (2022)

The GT1-TPS Structural Domain Protein From Haemonchus contortus Could Be Suppressive Antigen of Goat PBMCs
por: Wen, Zhaohai, et al.
Publicado: (2022)

Adhesion of Toxoplasma gondii tachyzoite-infected vehicle leukocytes to capillary endothelial cells triggers timely parasite egression
por: Baba, Minami, et al.
Publicado: (2017)

Protective efficacy of Toxoplasma gondii GRA12 or GRA7 recombinant proteins encapsulated in PLGA nanoparticles against acute Toxoplasma gondii infection in mice
por: Sun, Hong-chao, et al.
Publicado: (2023)

Identification of excretory and secretory proteins from Haemonchus contortus inducing a Th9 immune response in goats
por: Liang, Meng, et al.
Publicado: (2022)

Characterization of Membrane-Associated Progesterone Receptor Component-2 (MAPRC2) from Trichinella spiralis and Its Interaction with Progesterone and Mifepristone
por: Aleem, Muhammad Tahir, et al.
Publicado: (2021)

The Neurotropic Parasite Toxoplasma Gondii Increases Dopamine Metabolism
por: Prandovszky, Emese, et al.
Publicado: (2011)

Parasite powerhouse: A review of the Toxoplasma gondii mitochondrion
por: Usey, Madelaine M., et al.
Publicado: (2022)

Effect of chitosan on Toxoplasma gondii infection: A systematic review
por: Cheraghipour, Kourosh, et al.
Publicado: (2020)

Characterization of a secreted macrophage migration inhibitory factor homologue of the parasitic nematode Haemonchus Contortus acting at the parasite-host cell interface
por: Wang, Yujian, et al.
Publicado: (2017)

A Novel α/β Hydrolase Domain Protein Derived From Haemonchus contortus Acts at the Parasite-Host Interface
por: Lu, Mingmin, et al.
Publicado: (2020)

Histidine acid phosphatase domain-containing protein from Haemonchus contortus is a stimulatory antigen for the Th1 immune response of goat PBMCs
por: Wen, Zhaohai, et al.
Publicado: (2022)

Transepithelial Migration of Toxoplasma gondii Is Linked to Parasite Motility and Virulence
por: Barragan, Antonio, et al.
Publicado: (2002)

Secretory traffic in the eukaryotic parasite Toxoplasma gondii : less is more
por: Joiner, Keith A., et al.
Publicado: (2002)

Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii
por: Pratt, Steven, et al.
Publicado: (2013)

Parasite Infiltration and Apoptosis in Spleen upon Toxoplasma gondii Infection
por: Lee, Su-Hwa, et al.
Publicado: (2019)

REVIEW OF DNA VACCINE APPROACHES AGAINST THE PARASITE TOXOPLASMA GONDII
por: Warner, Rosalie C., et al.
Publicado: (2021)

Viability of Toxoplasma gondii tachyzoites in different conditions for parasite transportation
por: Nguyen, Thi Thuy, et al.
Publicado: (2022)

Systematic identification of the lysine lactylation in the protozoan parasite Toxoplasma gondii
por: Zhao, Wei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7a2s4n2u141jjne35qhqesnkeo