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miR-519d-3p suppresses tumorigenicity and metastasis by inhibiting Bcl-w and HIF-1α in NSCLC
Bcl-w, a member of the Bcl-2 family, is highly expressed in various solid tumor, including lung cancer, suggesting that it is involved in cancer cell survival and carcinogenesis. Solid cancer-induced hypoxia has been reported to increase angiogenesis, growth factor, gene instability, invasion, and m...
Autores principales: | Choi, Jae Yeon, Seok, Hyun Jeong, Kim, Rae-Kwon, Choi, Mi Young, Lee, Su-Jae, Bae, In Hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430049/ https://www.ncbi.nlm.nih.gov/pubmed/34553025 http://dx.doi.org/10.1016/j.omto.2021.06.015 |
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