Cargando…

Established and Emerging Regulatory Roles of Eukaryotic Translation Initiation Factor 5B (eIF5B)

Translational control (TC) is one the crucial steps that dictate gene expression and alter the outcome of physiological process like programmed cell death, metabolism, and proliferation in a eukaryotic cell. TC occurs mainly at the translation initiation stage. The initiation factor eIF5B tightly re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chukka, Prakash Amruth Raj, Wetmore, Stacey D., Thakor, Nehal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430213/ https://www.ncbi.nlm.nih.gov/pubmed/34512736 http://dx.doi.org/10.3389/fgene.2021.737433

Ejemplares similares

Eukaryotic Initiation Factor 5B (eIF5B) Cooperates with eIF1A and eIF5 to Facilitate uORF2-Mediated Repression of ATF4 Translation
por: Ross, Joseph A., et al.
Publicado: (2018)

Eukaryotic initiation factor 5B (eIF5B) provides a critical cell survival switch to glioblastoma cells via regulation of apoptosis
por: Ross, Joseph A., et al.
Publicado: (2019)

The Role of the Eukaryotic Translation Initiation Factor 4E (eIF4E) in Neuropsychiatric Disorders
por: Amorim, Inês S., et al.
Publicado: (2018)

Differential Regulation of the Three Eukaryotic mRNA Translation Initiation Factor (eIF) 4Gs by the Proteasome
por: Alard, Amandine, et al.
Publicado: (2019)

Inhibition of Eukaryotic Translation Initiation Factor 5A (eIF5A) Hypusination Suppress p53 Translation and Alters the Association of eIF5A to the Ribosomes
por: Martella, Marianna, et al.
Publicado: (2020)

Eukaryotic initiation factor EIF-3.G augments mRNA translation efficiency to regulate neuronal activity
por: Blazie, Stephen M, et al.
Publicado: (2021)

eIF5B gates the transition from translation initiation to elongation
por: Wang, Jinfan, et al.
Publicado: (2019)

Implications of the Use of Eukaryotic Translation Initiation Factor 5A (eIF5A) for Prognosis and Treatment of Hepatocellular Carcinoma
por: Shek, Felix H., et al.
Publicado: (2012)

eIF2B promotes eIF5 dissociation from eIF2•GDP to facilitate guanine nucleotide exchange for translation initiation
por: Jennings, Martin D., et al.
Publicado: (2013)

eIF1A/eIF5B interaction network and its functions in translation initiation complex assembly and remodeling
por: Nag, Nabanita, et al.
Publicado: (2016)

Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome
por: Schmidt, Christian, et al.
Publicado: (2016)

IRES-mediated translation of cellular messenger RNA operates in eIF2α- independent manner during stress
por: Thakor, Nehal, et al.
Publicado: (2012)

Diversity of Eukaryotic Translational Initiation Factor eIF4E in Protists
por: Jagus, Rosemary, et al.
Publicado: (2012)

Identification of Intersubunit Domain Interactions within Eukaryotic Initiation Factor (eIF) 2B, the Nucleotide Exchange Factor for Translation Initiation
por: Reid, Peter J., et al.
Publicado: (2012)

Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex
por: Wang, Jinfan, et al.
Publicado: (2020)

Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation
por: Huang, Bridget Y., et al.
Publicado: (2020)

Eukaryotic Initiation Factor 2B (eIF2B) GEF Activity as a Diagnostic Tool for EIF2B-Related Disorders
por: Horzinski, Laetitia, et al.
Publicado: (2009)

The Prognostic Significance of Eukaryotic Translation Initiation Factors (eIFs) in Endometrial Cancer
por: Smolle, Maria Anna, et al.
Publicado: (2019)

The eukaryotic translation initiation factor eIF4E reprograms alternative splicing
por: Ghram, Mehdi, et al.
Publicado: (2023)

Upregulation of a novel eukaryotic translation initiation factor 5A (eIF5A) in dengue 2 virus-infected mosquito cells
por: Shih, Yu-Tzu, et al.
Publicado: (2010)

eIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning
por: Pisareva, Vera P., et al.
Publicado: (2014)

eIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning
Publicado: (2021)

Cellular mRNA recruits the ribosome via eIF3-PABP bridge to initiate internal translation
por: Thakor, Nehal, et al.
Publicado: (2016)

‘Ribozoomin’ – Translation Initiation from the Perspective of the Ribosome-bound Eukaryotic Initiation Factors (eIFs)
por: Valášek, Leoš Shivaya
Publicado: (2012)

Overexpression of Eukaryotic Translation Initiation Factor 5A2 (EIF5A2) Correlates with Cell Aggressiveness and Poor Survival in Gastric Cancer
por: Meng, Qing-Bin, et al.
Publicado: (2015)

Eukaryotic translation initiation factor 5A2 (eIF5A2) regulates chemoresistance in colorectal cancer through epithelial mesenchymal transition
por: Bao, Ying, et al.
Publicado: (2015)

Specific mechanisms of translation initiation in higher eukaryotes: the eIF4G2 story
por: Shestakova, Ekaterina D., et al.
Publicado: (2023)

Evolutionary conserved role of eukaryotic translation factor eIF5A in the regulation of actin-nucleating formins
por: Muñoz-Soriano, Verónica, et al.
Publicado: (2017)

Role of Eukaryotic Initiation Factors during Cellular Stress and Cancer Progression
por: Sharma, Divya Khandige, et al.
Publicado: (2016)

Understanding and Targeting the Eukaryotic Translation Initiation Factor eIF4E in Head and Neck Cancer
por: Culjkovic, Biljana, et al.
Publicado: (2009)

The eukaryotic translation initiation factor eIF4E wears a “cap” for many occasions
por: Borden, Katherine L. B.
Publicado: (2016)

Overexpression of eukaryotic initiation factor 5A (eIF5A) affects susceptibility to benznidazole in Trypanosoma cruzi populations
por: Moreira, Douglas de Souza, et al.
Publicado: (2018)

The eukaryotic initiation factor 5A (eIF5A1), the molecule, mechanisms and recent insights into the pathophysiological roles
por: Tauc, Michel, et al.
Publicado: (2021)

Eukaryotic translation initiation factor eIF5 promotes the accuracy of start codon recognition by regulating Pi release and conformational transitions of the preinitiation complex
por: Saini, Adesh K., et al.
Publicado: (2015)

eIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B
por: Kim, Eunah, et al.
Publicado: (2018)

Eukaryotic translation initiation factor 5A in the pathogenesis of cancers
por: Ning, Liang, et al.
Publicado: (2020)

Expression profile of translation initiation factor eIF2B5 in diffuse large B-cell lymphoma and its correlation to clinical outcome
por: Unterluggauer, Julia J., et al.
Publicado: (2018)

RNA interference-mediated silencing of eukaryotic translation initiation factor 3, subunit B (EIF3B) gene expression inhibits proliferation of colon cancer cells
por: Wang, Zheng, et al.
Publicado: (2012)

Eukaryotic translation initiation factor 3 subunit G (EIF3G) resensitized HCT116/5-Fu to 5-fluorouracil (5-Fu) via inhibition of MRP and MDR1
por: Yang, Chenggang, et al.
Publicado: (2018)

eIF4B, eIF4G and RNA regulate eIF4A activity in translation initiation by modulating the eIF4A conformational cycle
por: Harms, Ulf, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ashv9bsj1dsg0m49p8hfe441p0