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Chronic Intermittent Hypoxia Reduces the Effects of Glucosteroid in Asthma via Activating the p38 MAPK Signaling Pathway

AIMS: Obstructive sleep apnea (OSA) is a risk factor for steroid-resistant (SR) asthma. However, the underlying mechanism is not well defined. This study aimed to investigate how chronic intermittent hypoxia (CIH), the main pathophysiology of OSA, influenced the effects of glucocorticoids (GCs) on a...

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Detalles Bibliográficos
Autores principales:	Liang, Li, Gu, Xin, Shen, Hai Ji, Shi, Yu Heng, Li, Yao, Zhang, Jie, Chen, Yan Yan, Chen, Zhen He, Ma, Jia Yun, Li, Qing Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430218/ https://www.ncbi.nlm.nih.gov/pubmed/34512379 http://dx.doi.org/10.3389/fphys.2021.703281

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