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Autophagy Induces Expression of IL-6 in Human Periodontal Ligament Fibroblasts Under Mechanical Load and Overload and Effects Osteoclastogenesis in vitro

Objective: Autophagy is an important cellular adaptation mechanism to mechanical stress. In animal experiments, inhibition of autophagy during orthodontic tooth movement triggered increased expression of inflammation-related genes and decreased bone density. The aim of this study was to investigate...

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Detalles Bibliográficos
Autores principales: Mayr, Alexandra, Marciniak, Jana, Eggers, Benedikt, Blawat, Kim, Wildenhof, Jan, Bastos Craveiro, Rogerio, Wolf, Michael, Deschner, James, Jäger, Andreas, Beisel-Memmert, Svenja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430222/
https://www.ncbi.nlm.nih.gov/pubmed/34512388
http://dx.doi.org/10.3389/fphys.2021.716441

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