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Secondary Attack Rate among Non-Spousal Household Contacts of Coronavirus Disease 2019 in Tsuchiura, Japan, August 2020–February 2021

Household secondary attack rate (HSAR) by risk factor might have a higher transmission rate between spouses. We investigated risk factors for the HSAR among non-spousal household contacts of patients with coronavirus disease 2019 (COVID-19). We studied household contacts of index cases of COVID-19 i...

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Autores principales: Ogata, Tsuyoshi, Irie, Fujiko, Ogawa, Eiko, Ujiie, Shifuko, Seki, Aina, Wada, Koji, Tanaka, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430497/
https://www.ncbi.nlm.nih.gov/pubmed/34501511
http://dx.doi.org/10.3390/ijerph18178921
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author Ogata, Tsuyoshi
Irie, Fujiko
Ogawa, Eiko
Ujiie, Shifuko
Seki, Aina
Wada, Koji
Tanaka, Hideo
author_facet Ogata, Tsuyoshi
Irie, Fujiko
Ogawa, Eiko
Ujiie, Shifuko
Seki, Aina
Wada, Koji
Tanaka, Hideo
author_sort Ogata, Tsuyoshi
collection PubMed
description Household secondary attack rate (HSAR) by risk factor might have a higher transmission rate between spouses. We investigated risk factors for the HSAR among non-spousal household contacts of patients with coronavirus disease 2019 (COVID-19). We studied household contacts of index cases of COVID-19 in Tsuchiura, Japan, from August 2020 through February 2021. The HSARs of the whole household contacts and non-spousal household contacts were calculated and compared across risk factors. We used a generalized linear mixed regression model for multivariate analysis. We enrolled 496 household contacts of 236 index COVID-19 cases. The HSAR was higher for spousal household contacts (37.8%) than for other contacts (21.2%). The HSAR was lower for non-spousal household contacts with a household size (number of household members) of two (18.2%), compared to the HSAR for contacts with a household size ≥4. The HSAR was higher for non-spousal household contacts of index patients with ≥3 days of diagnostic delay (period between onset and diagnosis) (26.0%) compared to those with ≤2 days’ delay (12.5%) (p = 0.033). Among non-spousal household contacts, the HSAR was low for those with a household size of two and was high for contacts of index patients with a long diagnostic delay.
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spelling pubmed-84304972021-09-11 Secondary Attack Rate among Non-Spousal Household Contacts of Coronavirus Disease 2019 in Tsuchiura, Japan, August 2020–February 2021 Ogata, Tsuyoshi Irie, Fujiko Ogawa, Eiko Ujiie, Shifuko Seki, Aina Wada, Koji Tanaka, Hideo Int J Environ Res Public Health Article Household secondary attack rate (HSAR) by risk factor might have a higher transmission rate between spouses. We investigated risk factors for the HSAR among non-spousal household contacts of patients with coronavirus disease 2019 (COVID-19). We studied household contacts of index cases of COVID-19 in Tsuchiura, Japan, from August 2020 through February 2021. The HSARs of the whole household contacts and non-spousal household contacts were calculated and compared across risk factors. We used a generalized linear mixed regression model for multivariate analysis. We enrolled 496 household contacts of 236 index COVID-19 cases. The HSAR was higher for spousal household contacts (37.8%) than for other contacts (21.2%). The HSAR was lower for non-spousal household contacts with a household size (number of household members) of two (18.2%), compared to the HSAR for contacts with a household size ≥4. The HSAR was higher for non-spousal household contacts of index patients with ≥3 days of diagnostic delay (period between onset and diagnosis) (26.0%) compared to those with ≤2 days’ delay (12.5%) (p = 0.033). Among non-spousal household contacts, the HSAR was low for those with a household size of two and was high for contacts of index patients with a long diagnostic delay. MDPI 2021-08-25 /pmc/articles/PMC8430497/ /pubmed/34501511 http://dx.doi.org/10.3390/ijerph18178921 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ogata, Tsuyoshi
Irie, Fujiko
Ogawa, Eiko
Ujiie, Shifuko
Seki, Aina
Wada, Koji
Tanaka, Hideo
Secondary Attack Rate among Non-Spousal Household Contacts of Coronavirus Disease 2019 in Tsuchiura, Japan, August 2020–February 2021
title Secondary Attack Rate among Non-Spousal Household Contacts of Coronavirus Disease 2019 in Tsuchiura, Japan, August 2020–February 2021
title_full Secondary Attack Rate among Non-Spousal Household Contacts of Coronavirus Disease 2019 in Tsuchiura, Japan, August 2020–February 2021
title_fullStr Secondary Attack Rate among Non-Spousal Household Contacts of Coronavirus Disease 2019 in Tsuchiura, Japan, August 2020–February 2021
title_full_unstemmed Secondary Attack Rate among Non-Spousal Household Contacts of Coronavirus Disease 2019 in Tsuchiura, Japan, August 2020–February 2021
title_short Secondary Attack Rate among Non-Spousal Household Contacts of Coronavirus Disease 2019 in Tsuchiura, Japan, August 2020–February 2021
title_sort secondary attack rate among non-spousal household contacts of coronavirus disease 2019 in tsuchiura, japan, august 2020–february 2021
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430497/
https://www.ncbi.nlm.nih.gov/pubmed/34501511
http://dx.doi.org/10.3390/ijerph18178921
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