Photodynamic Therapy: A Compendium of Latest Reviews

SIMPLE SUMMARY: In recent years, numerous general and specific reviews about photodynamic therapy and related subtopics have been published. The diversity of reviews is broad, including many different complex topics and disciplines. In this work, we aim to summarize and compile the latest reviews covering the whole photodynamic therapy field. Specifically, the most important reviews of the last two decades are described. Additionally, some of the key issues and main conclusions detected in these reviews are included. We hope this work will serve as a guide and starting point for researchers to delve further into specific topics and formulate research questions. ABSTRACT: Photodynamic therapy (PDT) is a promising therapy against cancer. Even though it has been investigated for more than 100 years, scientific publications have grown exponentially in the last two decades. For this reason, we present a brief compendium of reviews of the last two decades classified under different topics, namely, overviews, reviews about specific cancers, and meta-analyses of photosensitisers, PDT mechanisms, dosimetry, and light sources. The key issues and main conclusions are summarized, including ways and means to improve therapy and outcomes. Due to the broad scope of this work and it being the first time that a compendium of the latest reviews has been performed for PDT, it may be of interest to a wide audience.