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Phosphorylation of SARS-CoV-2 Orf9b Regulates Its Targeting to Two Binding Sites in TOM70 and Recruitment of Hsp90

SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is the causative agent of the COVID19 pandemic. The SARS-CoV-2 genome encodes for a small accessory protein termed Orf9b, which targets the mitochondrial outer membrane protein TOM70 in infected cells. TOM70 is involved in a signaling casc...

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Detalles Bibliográficos
Autores principales:	Brandherm, Lukas, Kobaš, Antonio Mario, Klöhn, Mara, Brüggemann, Yannick, Pfaender, Stephanie, Rassow, Joachim, Kreimendahl, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430508/ https://www.ncbi.nlm.nih.gov/pubmed/34502139 http://dx.doi.org/10.3390/ijms22179233

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