Cargando…

Modeling In Vitro Osteoarthritis Phenotypes in a Vascularized Bone Model Based on a Bone-Marrow Derived Mesenchymal Cell Line and Endothelial Cells

The subchondral bone and its associated vasculature play an important role in the onset of osteoarthritis (OA). Integration of different aspects of the OA environment into multi-cellular and complex human, in vitro models is therefore needed to properly represent the pathology. In this study, we exp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pirosa, Alessandro, Tankus, Esma Bahar, Mainardi, Andrea, Occhetta, Paola, Dönges, Laura, Baum, Cornelia, Rasponi, Marco, Martin, Ivan, Barbero, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430538/ https://www.ncbi.nlm.nih.gov/pubmed/34502489 http://dx.doi.org/10.3390/ijms22179581

Ejemplares similares

Chondrocyte Hypertrophy in Osteoarthritis: Mechanistic Studies and Models for the Identification of New Therapeutic Strategies
por: Chawla, Shikha, et al.
Publicado: (2022)

Animal Models of Bone Marrow Lesions in Osteoarthritis
por: Bowen, Andrew, et al.
Publicado: (2022)

Engineering in-vitro stem cell-based vascularized bone models for drug screening and predictive toxicology
por: Pirosa, Alessandro, et al.
Publicado: (2018)

A dynamic microscale mid-throughput fibrosis model to investigate the effects of different ratios of cardiomyocytes and fibroblasts
por: Mainardi, Andrea, et al.
Publicado: (2021)

Intervertebral Disc-on-a-Chip as Advanced In Vitro Model for Mechanobiology Research and Drug Testing: A Review and Perspective
por: Mainardi, Andrea, et al.
Publicado: (2022)

Modeling appendicular skeletal cartilage development with modified high-density micromass cultures of adult human bone marrow-derived mesenchymal progenitor cells
por: Pirosa, Alessandro, et al.
Publicado: (2019)

In Vivo Vascularization of Endothelial Cells Derived from Bone Marrow Mesenchymal Stem Cells in SCID Mouse Model
por: Allameh, Abdolamir, et al.
Publicado: (2016)

Characterization of vascular endothelial progenitor cells from chicken bone marrow
por: Bai, Chunyu, et al.
Publicado: (2012)

IFNα-mediated remodeling of endothelial cells in the bone marrow niche
por: Prendergast, Áine M., et al.
Publicado: (2017)

Method for in vitro differentiation of bone marrow mesenchymal stem cells into endothelial progenitor cells and vascular endothelial cells
por: Wang, Qihong, et al.
Publicado: (2016)

Reprogramming Bone Marrow Stem Cells to Functional Endothelial Cells in a Mini Pig Animal Model
por: Schlegel, Franziska, et al.
Publicado: (2017)

Fabrication and Characterization of PCL/HA Filament as a 3D Printing Material Using Thermal Extrusion Technology for Bone Tissue Engineering
por: Wang, Fengze, et al.
Publicado: (2022)

Characterization and assessment of lung and bone marrow derived endothelial cells and their bone regenerative potential
por: Moraes de Lima Perini, Mariana, et al.
Publicado: (2022)

Bone marrow as a secondary lymphoid organ: mature T-cell subsets in bone marrow from rheumatoid arthritis and osteoarthritis patients
por: Warnawin, E, et al.
Publicado: (2005)

Endothelial cells influence the osteogenic potential of bone marrow stromal cells
por: Xue, Ying, et al.
Publicado: (2009)

Endothelial Progenitor Cells Do Not Originate From the Bone Marrow
por: Fujisawa, Takeshi, et al.
Publicado: (2019)

Plasmodium vivax Gametocytes Adherence to Bone Marrow Endothelial Cells
por: Salazar Alvarez, Luis Carlos, et al.
Publicado: (2021)

Bone marrow-derived cells do not repair endothelium in a mouse model of chronic endothelial cell dysfunction
por: Perry, Tashera E., et al.
Publicado: (2009)

PEDF promotes the repair of bone marrow endothelial cell injury and accelerates hematopoietic reconstruction after bone marrow transplantation
por: Ju, Wen, et al.
Publicado: (2020)

Impaired Endothelial Progenitor Cell Mobilization and Dysfunctional Bone Marrow Stroma in Diabetes Mellitus
por: Westerweel, Peter E., et al.
Publicado: (2013)

The bone marrow pericyte: an orchestrator of vascular niche
por: Mangialardi, Giuseppe, et al.
Publicado: (2016)

Bone Marrow Endothelial Progenitor Cells Are the Cellular Mediators of Pulmonary Hypertension in the Murine Monocrotaline Injury Model
por: Aliotta, Jason M., et al.
Publicado: (2017)

The New Role of CD163 in the Differentiation of Bone Marrow Stromal Cells into Vascular Endothelial-Like Cells
por: Lu, Wei, et al.
Publicado: (2016)

Silencing of RBP-JK promotes the differentiation of bone marrow mesenchymal stem cells into vascular endothelial cells
por: Luo, Zhengliang, et al.
Publicado: (2020)

Mesenchymal Stem Cell Alterations in Bone Marrow Lesions in Patients With Hip Osteoarthritis
por: Campbell, T. Mark, et al.
Publicado: (2016)

Therapeutic effects of bone marrow mesenchymal stem cells‐derived exosomes on osteoarthritis
por: Jin, Yi, et al.
Publicado: (2021)

Cilostazol Activates Function of Bone Marrow-Derived Endothelial Progenitor Cell for Re-endothelialization in a Carotid Balloon Injury Model
por: Kawabe-Yako, Rie, et al.
Publicado: (2011)

Bone marrow mesenchymal stem cell-derived exosomes protect cartilage damage and relieve knee osteoarthritis pain in a rat model of osteoarthritis
por: He, Lei, et al.
Publicado: (2020)

Bone Marrow Aspirate Concentrate: Its Uses in Osteoarthritis
por: Kim, Gi Beom, et al.
Publicado: (2020)

Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow
por: Xu, Chunliang, et al.
Publicado: (2018)

Bone Marrow Endothelial Cells Increase Prostate Cancer Cell Apoptosis in 3D Triculture Model of Reactive Stroma
por: Sablatura, Lindsey K., et al.
Publicado: (2022)

The characteristics of bone marrow-derived endothelial progenitor cells and their effect on glioma
por: Zhang, She-Hong, et al.
Publicado: (2012)

Bone marrow transplant model to study articular cartilage repair
por: Sergijenko, Ana, et al.
Publicado: (2015)

Noninvasive Tracking of Hematopoietic Stem Cells in a Bone Marrow Transplant Model
por: Oliveira, Fernando A., et al.
Publicado: (2020)

The Role of Bone Marrow-Derived Cells during Ectopic Bone Formation of Mouse Femoral Muscle in GFP Mouse Bone Marrow Transplantation Model
por: Takabatake, Kiyofumi, et al.
Publicado: (2018)

The osteoarthritis bone score (OABS): a new histological scoring system for the characterisation of bone marrow lesions in osteoarthritis
por: Koushesh, S., et al.
Publicado: (2022)

Autologous Bone-Marrow Mesenchymal Stem Cell Implantation and Endothelial Function in a Rabbit Ischemic Limb Model
por: Mikami, Shinsuke, et al.
Publicado: (2013)

Distribution of Bone-Marrow-Derived Endothelial and Immune Cells in a Murine Colitis-Associated Colorectal Cancer Model
por: Xiao, Chuan-Xing, et al.
Publicado: (2013)

Repair of bone defects with prefabricated vascularized bone grafts and double-labeled bone marrow-derived mesenchymal stem cells in a rat model
por: Jiang, Xiao-Rui, et al.
Publicado: (2017)

High-Throughput Microfluidic Platform for 3D Cultures of Mesenchymal Stem Cells, Towards Engineering Developmental Processes
por: Occhetta, Paola, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_81b1k4crk1j8csirqd6u2h03q1