Cargando…
Early Bone Healing on Hydroxyapatite-Coated and Chemically-Modified Hydrophilic Implant Surfaces in an Ovine Model
Implant topography affects early peri-implant bone healing by changing the osteoconduction rate in the surrounding biological environment. Implant surfaces have been designed to promote faster and stronger bone formation for rapid and stable prosthesis loading. Early peri-implant bone healing has be...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430562/ https://www.ncbi.nlm.nih.gov/pubmed/34502270 http://dx.doi.org/10.3390/ijms22179361 |
_version_ | 1783750732442238976 |
---|---|
author | Ajami, Elnaz Fu, Cong Wen, Hai Bo Bassett, Jeffrey Park, Sun Jin Pollard, Marie |
author_facet | Ajami, Elnaz Fu, Cong Wen, Hai Bo Bassett, Jeffrey Park, Sun Jin Pollard, Marie |
author_sort | Ajami, Elnaz |
collection | PubMed |
description | Implant topography affects early peri-implant bone healing by changing the osteoconduction rate in the surrounding biological environment. Implant surfaces have been designed to promote faster and stronger bone formation for rapid and stable prosthesis loading. Early peri-implant bone healing has been observed with a sandblasted, acid-etched implant that was chemically modified to be hydrophilic (cmSLA). The present study investigates whether early peri-implant bone healing extends to a rough surface implant with a high crystalline hydroxyapatite surface (TSV MP-1 HA). Three implants were randomly placed in porous trabecular bone within both medial femoral condyles of 10 sheep. Early peri-implant bone stability was measured at 3- and 6-weeks healing time following implant insertion. Results indicated a similar implant stability quotient between the implants at insertion and over time. The significant increase over time of reverse torque values with respect to insertion torque (p < 0.001) did not differ between the implants. However, the bone-to-implant contact of TSV MP-1 HA was significantly higher than that of cmSLA implants at 6 weeks (p < 0.01). These data validate previous findings of a hydrophilic implant surface and extend the observation of early osseointegration to a rough surface implant in porous trabecular bone. |
format | Online Article Text |
id | pubmed-8430562 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84305622021-09-11 Early Bone Healing on Hydroxyapatite-Coated and Chemically-Modified Hydrophilic Implant Surfaces in an Ovine Model Ajami, Elnaz Fu, Cong Wen, Hai Bo Bassett, Jeffrey Park, Sun Jin Pollard, Marie Int J Mol Sci Article Implant topography affects early peri-implant bone healing by changing the osteoconduction rate in the surrounding biological environment. Implant surfaces have been designed to promote faster and stronger bone formation for rapid and stable prosthesis loading. Early peri-implant bone healing has been observed with a sandblasted, acid-etched implant that was chemically modified to be hydrophilic (cmSLA). The present study investigates whether early peri-implant bone healing extends to a rough surface implant with a high crystalline hydroxyapatite surface (TSV MP-1 HA). Three implants were randomly placed in porous trabecular bone within both medial femoral condyles of 10 sheep. Early peri-implant bone stability was measured at 3- and 6-weeks healing time following implant insertion. Results indicated a similar implant stability quotient between the implants at insertion and over time. The significant increase over time of reverse torque values with respect to insertion torque (p < 0.001) did not differ between the implants. However, the bone-to-implant contact of TSV MP-1 HA was significantly higher than that of cmSLA implants at 6 weeks (p < 0.01). These data validate previous findings of a hydrophilic implant surface and extend the observation of early osseointegration to a rough surface implant in porous trabecular bone. MDPI 2021-08-28 /pmc/articles/PMC8430562/ /pubmed/34502270 http://dx.doi.org/10.3390/ijms22179361 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ajami, Elnaz Fu, Cong Wen, Hai Bo Bassett, Jeffrey Park, Sun Jin Pollard, Marie Early Bone Healing on Hydroxyapatite-Coated and Chemically-Modified Hydrophilic Implant Surfaces in an Ovine Model |
title | Early Bone Healing on Hydroxyapatite-Coated and Chemically-Modified Hydrophilic Implant Surfaces in an Ovine Model |
title_full | Early Bone Healing on Hydroxyapatite-Coated and Chemically-Modified Hydrophilic Implant Surfaces in an Ovine Model |
title_fullStr | Early Bone Healing on Hydroxyapatite-Coated and Chemically-Modified Hydrophilic Implant Surfaces in an Ovine Model |
title_full_unstemmed | Early Bone Healing on Hydroxyapatite-Coated and Chemically-Modified Hydrophilic Implant Surfaces in an Ovine Model |
title_short | Early Bone Healing on Hydroxyapatite-Coated and Chemically-Modified Hydrophilic Implant Surfaces in an Ovine Model |
title_sort | early bone healing on hydroxyapatite-coated and chemically-modified hydrophilic implant surfaces in an ovine model |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430562/ https://www.ncbi.nlm.nih.gov/pubmed/34502270 http://dx.doi.org/10.3390/ijms22179361 |
work_keys_str_mv | AT ajamielnaz earlybonehealingonhydroxyapatitecoatedandchemicallymodifiedhydrophilicimplantsurfacesinanovinemodel AT fucong earlybonehealingonhydroxyapatitecoatedandchemicallymodifiedhydrophilicimplantsurfacesinanovinemodel AT wenhaibo earlybonehealingonhydroxyapatitecoatedandchemicallymodifiedhydrophilicimplantsurfacesinanovinemodel AT bassettjeffrey earlybonehealingonhydroxyapatitecoatedandchemicallymodifiedhydrophilicimplantsurfacesinanovinemodel AT parksunjin earlybonehealingonhydroxyapatitecoatedandchemicallymodifiedhydrophilicimplantsurfacesinanovinemodel AT pollardmarie earlybonehealingonhydroxyapatitecoatedandchemicallymodifiedhydrophilicimplantsurfacesinanovinemodel |