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Low Doses of Ketamine and Melatonin in Combination Produce Additive Antidepressant-like Effects in Mice
Major depressive disorder is a disabling disease with the number of affected individuals increasing each year. Current antidepressant treatments take between three to six weeks to be effective with forty percent of patients being resistant to treatment, making it necessary to search for new antidepr...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430602/ https://www.ncbi.nlm.nih.gov/pubmed/34502152 http://dx.doi.org/10.3390/ijms22179225 |