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Impaired Differentiation of Highly Proliferative ICOS(+)-Tregs Is Involved in the Transition from Low to High Disease Activity in Systemic Lupus Erythematosus (SLE) Patients

Dysregulations in the differentiation of CD4(+)-regulatory-T-cells (Tregs) and CD4(+)-responder-T-cells (Tresps) are involved in the development of active systemic lupus erythematosus (SLE). Three differentiation pathways of highly proliferative inducible costimulatory molecule (ICOS)(+)- and less p...

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Detalles Bibliográficos
Autores principales: Kälble, Florian, Wu, Lisa, Lorenz, Hanns-Martin, Zeier, Martin, Schaier, Matthias, Steinborn, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430608/
https://www.ncbi.nlm.nih.gov/pubmed/34502409
http://dx.doi.org/10.3390/ijms22179501

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