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Impaired Differentiation of Highly Proliferative ICOS(+)-Tregs Is Involved in the Transition from Low to High Disease Activity in Systemic Lupus Erythematosus (SLE) Patients
Dysregulations in the differentiation of CD4(+)-regulatory-T-cells (Tregs) and CD4(+)-responder-T-cells (Tresps) are involved in the development of active systemic lupus erythematosus (SLE). Three differentiation pathways of highly proliferative inducible costimulatory molecule (ICOS)(+)- and less p...
Autores principales: | Kälble, Florian, Wu, Lisa, Lorenz, Hanns-Martin, Zeier, Martin, Schaier, Matthias, Steinborn, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430608/ https://www.ncbi.nlm.nih.gov/pubmed/34502409 http://dx.doi.org/10.3390/ijms22179501 |
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