ATG101 Degradation by HUWE1-Mediated Ubiquitination Impairs Autophagy and Reduces Survival in Cancer Cells

Autophagy is a critical cytoprotective mechanism against stress, which is initiated by the protein kinase Unc-51-like kinase 1 (ULK1) complex. Autophagy plays a role in both inhibiting the progression of diseases and facilitating pathogenesis, so it is critical to elucidate the mechanisms regulating...

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Detalles Bibliográficos
Autores principales: Lee, JaeYung, Kim, Jiyea, Shin, Jeongeun, Kang, YongHyun, Choi, Jungwon, Cheong, Heesun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430637/
https://www.ncbi.nlm.nih.gov/pubmed/34502089
http://dx.doi.org/10.3390/ijms22179182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430637/
https://www.ncbi.nlm.nih.gov/pubmed/34502089
http://dx.doi.org/10.3390/ijms22179182

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