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TCR Clonality and Genomic Instability Signatures as Prognostic Biomarkers in High Grade Serous Ovarian Cancer

SIMPLE SUMMARY: High-grade serous ovarian carcinoma (HGSC) could be analyzed with a molecular stratification defined by different genomic instability signatures associated with specific mutational process and prognostic biomarkers. Immune infiltrate is known to be a robust biomarker in HGSC. We aime...

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Detalles Bibliográficos
Autores principales: Lecuelle, Julie, Boidot, Romain, Mananet, Hugo, Derangère, Valentin, Albuisson, Juliette, Goussot, Vincent, Arnould, Laurent, Tharin, Zoé, Ray Coquard, Isabelle, Ghiringhelli, François, Truntzer, Caroline, Fumet, Jean-David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430641/
https://www.ncbi.nlm.nih.gov/pubmed/34503204
http://dx.doi.org/10.3390/cancers13174394