Cargando…

Effectiveness of Pulmonary Rehabilitation in Severe and Critically Ill COVID-19 Patients: A Controlled Study

Background: Severe and critically ill COVID-19 patients frequently need pulmonary rehabilitation (PR) after hospitalization. However, little is known about the effectiveness of PR in COVID-19 patients. Methods: We compared the performances in the six-min walk test (6MWT), chronic respiratory questio...

Descripción completa

Detalles Bibliográficos
Autores principales: Büsching, Gilbert, Zhang, Zhongxing, Schmid, Jean-Paul, Sigrist, Thomas, Khatami, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430691/
https://www.ncbi.nlm.nih.gov/pubmed/34501549
http://dx.doi.org/10.3390/ijerph18178956
_version_ 1783750762832068608
author Büsching, Gilbert
Zhang, Zhongxing
Schmid, Jean-Paul
Sigrist, Thomas
Khatami, Ramin
author_facet Büsching, Gilbert
Zhang, Zhongxing
Schmid, Jean-Paul
Sigrist, Thomas
Khatami, Ramin
author_sort Büsching, Gilbert
collection PubMed
description Background: Severe and critically ill COVID-19 patients frequently need pulmonary rehabilitation (PR) after hospitalization. However, little is known about the effectiveness of PR in COVID-19 patients. Methods: We compared the performances in the six-min walk test (6MWT), chronic respiratory questionnaire (CRQ), and Functional Independence Measure (FIM) from inpatient PR between 51 COVID-19 patients and 51 other patients with common pneumonia. We used multivariate linear regression controlled for baseline values at entrance, age, sex, and cumulative illness rating scale. The odds ratios (ORs) of non-improvement/improvement in 6MWT (>30-m) and CRQ (>10-point) at discharge were compared between the two groups (Fisher’s exact test). Results: The two groups had similar improvements in 6MWT and CRQ, but the COVID-19 group achieved a 4-point higher FIM (p-value = 0.004). The OR of non-improvement/improvement in 6MWT was 0.30 (p-value = 0.13) between COVID-19 and controls; however, the odds of non-improvement in CRQ tended to be 3.02 times higher (p-value = 0.075) in COVID-19 patients. Severe and critical COVID-19 patients had similar rehabilitation outcomes. Conclusions: Inpatient PR can effectively improve physical functions and life quality in COVID-19 patients, irrespective of disease severity. Whether the relatively low gains in CRQ is an indicator of chronic disease development in COVID-19 patients needs further studies.
format Online
Article
Text
id pubmed-8430691
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-84306912021-09-11 Effectiveness of Pulmonary Rehabilitation in Severe and Critically Ill COVID-19 Patients: A Controlled Study Büsching, Gilbert Zhang, Zhongxing Schmid, Jean-Paul Sigrist, Thomas Khatami, Ramin Int J Environ Res Public Health Article Background: Severe and critically ill COVID-19 patients frequently need pulmonary rehabilitation (PR) after hospitalization. However, little is known about the effectiveness of PR in COVID-19 patients. Methods: We compared the performances in the six-min walk test (6MWT), chronic respiratory questionnaire (CRQ), and Functional Independence Measure (FIM) from inpatient PR between 51 COVID-19 patients and 51 other patients with common pneumonia. We used multivariate linear regression controlled for baseline values at entrance, age, sex, and cumulative illness rating scale. The odds ratios (ORs) of non-improvement/improvement in 6MWT (>30-m) and CRQ (>10-point) at discharge were compared between the two groups (Fisher’s exact test). Results: The two groups had similar improvements in 6MWT and CRQ, but the COVID-19 group achieved a 4-point higher FIM (p-value = 0.004). The OR of non-improvement/improvement in 6MWT was 0.30 (p-value = 0.13) between COVID-19 and controls; however, the odds of non-improvement in CRQ tended to be 3.02 times higher (p-value = 0.075) in COVID-19 patients. Severe and critical COVID-19 patients had similar rehabilitation outcomes. Conclusions: Inpatient PR can effectively improve physical functions and life quality in COVID-19 patients, irrespective of disease severity. Whether the relatively low gains in CRQ is an indicator of chronic disease development in COVID-19 patients needs further studies. MDPI 2021-08-25 /pmc/articles/PMC8430691/ /pubmed/34501549 http://dx.doi.org/10.3390/ijerph18178956 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Büsching, Gilbert
Zhang, Zhongxing
Schmid, Jean-Paul
Sigrist, Thomas
Khatami, Ramin
Effectiveness of Pulmonary Rehabilitation in Severe and Critically Ill COVID-19 Patients: A Controlled Study
title Effectiveness of Pulmonary Rehabilitation in Severe and Critically Ill COVID-19 Patients: A Controlled Study
title_full Effectiveness of Pulmonary Rehabilitation in Severe and Critically Ill COVID-19 Patients: A Controlled Study
title_fullStr Effectiveness of Pulmonary Rehabilitation in Severe and Critically Ill COVID-19 Patients: A Controlled Study
title_full_unstemmed Effectiveness of Pulmonary Rehabilitation in Severe and Critically Ill COVID-19 Patients: A Controlled Study
title_short Effectiveness of Pulmonary Rehabilitation in Severe and Critically Ill COVID-19 Patients: A Controlled Study
title_sort effectiveness of pulmonary rehabilitation in severe and critically ill covid-19 patients: a controlled study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430691/
https://www.ncbi.nlm.nih.gov/pubmed/34501549
http://dx.doi.org/10.3390/ijerph18178956
work_keys_str_mv AT buschinggilbert effectivenessofpulmonaryrehabilitationinsevereandcriticallyillcovid19patientsacontrolledstudy
AT zhangzhongxing effectivenessofpulmonaryrehabilitationinsevereandcriticallyillcovid19patientsacontrolledstudy
AT schmidjeanpaul effectivenessofpulmonaryrehabilitationinsevereandcriticallyillcovid19patientsacontrolledstudy
AT sigristthomas effectivenessofpulmonaryrehabilitationinsevereandcriticallyillcovid19patientsacontrolledstudy
AT khatamiramin effectivenessofpulmonaryrehabilitationinsevereandcriticallyillcovid19patientsacontrolledstudy