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SHP2 as a Potential Therapeutic Target in Diffuse-Type Gastric Carcinoma Addicted to Receptor Tyrosine Kinase Signaling

SIMPLE SUMMARY: Diffuse-type gastric carcinoma (DGC) is characterized by rapid infiltrative growth associated with massive stroma and frequent peritoneal dissemination, which leads to poor patient outcomes. In this study, we found that the oncogenic tyrosine phosphatase SHP2 is tyrosine-phosphorylat...

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Detalles Bibliográficos
Autores principales:	Nagamura, Yuko, Miyazaki, Makoto, Nagano, Yoshiko, Tomiyama, Arata, Ohki, Rieko, Yanagihara, Kazuyoshi, Sakai, Ryuichi, Yamaguchi, Hideki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430696/ https://www.ncbi.nlm.nih.gov/pubmed/34503119 http://dx.doi.org/10.3390/cancers13174309

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