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In Vitro and In Vivo Effects of SerpinA1 on the Modulation of Transthyretin Proteolysis

Transthyretin (TTR) proteolysis has been recognized as a complementary mechanism contributing to transthyretin-related amyloidosis (ATTR amyloidosis). Accordingly, amyloid deposits can be composed mainly of full-length TTR or contain a mixture of both cleaved and full-length TTR, particularly in the...

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Detalles Bibliográficos
Autores principales: Bezerra, Filipa, Niemietz, Christoph, Schmidt, Hartmut H. J., Zibert, Andree, Guo, Shuling, Monia, Brett P., Gonçalves, Paula, Saraiva, Maria João, Almeida, Maria Rosário
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430710/
https://www.ncbi.nlm.nih.gov/pubmed/34502397
http://dx.doi.org/10.3390/ijms22179488