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Glutamine Availability Controls BCR/Abl Protein Expression and Functional Phenotype of Chronic Myeloid Leukemia Cells Endowed with Stem/Progenitor Cell Potential

SIMPLE SUMMARY: In chronic myeloid leukemia (CML), a neoplasm brilliantly taken care of by a molecularly targeted therapeutic approach, the achievement of cure is nevertheless prevented by the maintenance of a small subset of treatment-resistant leukemia stem cells (LSCs), sustaining the so-called m...

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Detalles Bibliográficos
Autores principales: Poteti, Martina, Menegazzi, Giulio, Peppicelli, Silvia, Tusa, Ignazia, Cheloni, Giulia, Silvano, Angela, Mancini, Caterina, Biagioni, Alessio, Tubita, Alessandro, Mazure, Nathalie M., Lulli, Matteo, Rovida, Elisabetta, Dello Sbarba, Persio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430815/
https://www.ncbi.nlm.nih.gov/pubmed/34503182
http://dx.doi.org/10.3390/cancers13174372