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Germline CDH1 G212E Missense Variant: Combining Clinical, In Vitro and In Vivo Strategies to Unravel Disease Burden

SIMPLE SUMMARY: Hereditary diffuse gastric cancer (HDGC) is an inherited cancer syndrome associated with CDH1 germline mutations. The increasing detection of CDH1 genetic variants due to multigene panel testing poses a serious clinical challenge and urges the development of effective classification...

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Detalles Bibliográficos
Autores principales:	Figueiredo, Joana, Mercadillo, Fátima, Melo, Soraia, Barroso, Alicia, Gonçalves, Margarida, Díaz-Tasende, José, Carneiro, Patrícia, Robles, Luis, Colina, Francisco, Ibarrola, Carolina, Perea, José, Morais-de-Sá, Eurico, Seruca, Raquel, Urioste, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430832/ https://www.ncbi.nlm.nih.gov/pubmed/34503169 http://dx.doi.org/10.3390/cancers13174359

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