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A Mutation in DNA Polymerase α Rescues WEE1(KO) Sensitivity to HU

During DNA replication, the WEE1 kinase is responsible for safeguarding genomic integrity by phosphorylating and thus inhibiting cyclin-dependent kinases (CDKs), which are the driving force of the cell cycle. Consequentially, wee1 mutant plants fail to respond properly to problems arising during DNA...

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Detalles Bibliográficos
Autores principales: Eekhout, Thomas, Pedroza-Garcia, José Antonio, Kalhorzadeh, Pooneh, De Jaeger, Geert, De Veylder, Lieven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430855/
https://www.ncbi.nlm.nih.gov/pubmed/34502313
http://dx.doi.org/10.3390/ijms22179409