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A Mutation in DNA Polymerase α Rescues WEE1(KO) Sensitivity to HU
During DNA replication, the WEE1 kinase is responsible for safeguarding genomic integrity by phosphorylating and thus inhibiting cyclin-dependent kinases (CDKs), which are the driving force of the cell cycle. Consequentially, wee1 mutant plants fail to respond properly to problems arising during DNA...
Autores principales: | Eekhout, Thomas, Pedroza-Garcia, José Antonio, Kalhorzadeh, Pooneh, De Jaeger, Geert, De Veylder, Lieven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430855/ https://www.ncbi.nlm.nih.gov/pubmed/34502313 http://dx.doi.org/10.3390/ijms22179409 |
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