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MicroRNA-29a in Osteoblasts Represses High-Fat Diet-Mediated Osteoporosis and Body Adiposis through Targeting Leptin

Skeletal tissue involves systemic adipose tissue metabolism and energy expenditure. MicroRNA signaling controls high-fat diet (HFD)-induced bone and fat homeostasis dysregulation remains uncertain. This study revealed that transgenic overexpression of miR-29a under control of osteocalcin promoter in...

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Detalles Bibliográficos
Autores principales: Lian, Wei-Shiung, Wu, Re-Wen, Chen, Yu-Shan, Ko, Jih-Yang, Wang, Shao-Yu, Jahr, Holger, Wang, Feng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430888/
https://www.ncbi.nlm.nih.gov/pubmed/34502056
http://dx.doi.org/10.3390/ijms22179135