Cargando…

The Expression Profiles and Deregulation of UDP-Glycosyltransferase (UGT) Genes in Human Cancers and Their Association with Clinical Outcomes

SIMPLE SUMMARY: The human UDP-glycosyltransferase (UGT) superfamily plays a critical role in the metabolism of numerous endogenous and exogenous small lipophilic compounds, including carcinogens, drugs, and bioactive molecules with pro- or anti-cancer activity. Previous studies have documented the e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Dong Gui, Marri, Shashikanth, Mackenzie, Peter I., Hulin, Julie-Ann, McKinnon, Ross A., Meech, Robyn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430925/ https://www.ncbi.nlm.nih.gov/pubmed/34503303 http://dx.doi.org/10.3390/cancers13174491

Ejemplares similares

The Somatic Mutation Landscape of UDP-Glycosyltransferase (UGT) Genes in Human Cancers
por: Hu, Dong Gui, et al.
Publicado: (2022)

Novel Nine-Exon AR Transcripts (Exon 1/Exon 1b/Exons 2–8) in Normal and Cancerous Breast and Prostate Cells
por: Hu, Dong Gui, et al.
Publicado: (2016)

The Uridine diphosphate (UDP)-glycosyltransferases (UGTs) superfamily: the role in tumor cell metabolism
por: Liu, Wenyu, et al.
Publicado: (2023)

The Expression Profiles of ADME Genes in Human Cancers and Their Associations with Clinical Outcomes
por: Hu, Dong Gui, et al.
Publicado: (2020)

Integrative Transcriptomic Network Analysis of Butyrate Treated Colorectal Cancer Cells
por: Ali, Saira R., et al.
Publicado: (2021)

The unprecedented diversity of UGT94-family UDP-glycosyltransferases in Panax plants and their contribution to ginsenoside biosynthesis
por: Yang, Chengshuai, et al.
Publicado: (2020)

Characterization of the UDP-glycosyltransferase UGT72 Family in Poplar and Identification of Genes Involved in the Glycosylation of Monolignols
por: Speeckaert, Nathanael, et al.
Publicado: (2020)

UDP-Glycosyltransferases from the UGT344 Family Are Involved in Sulfoxaflor Resistance in Aphis gossypii Glover
por: Ma, Kangsheng, et al.
Publicado: (2021)

Genome-wide analysis of family-1 UDP glycosyltransferases (UGT) and identification of UGT genes for FHB resistance in wheat (Triticum aestivum L.)
por: He, Yi, et al.
Publicado: (2018)

UGT86C11 is a novel plant UDP-glycosyltransferase involved in labdane diterpene biosynthesis
por: Srivastava, Payal, et al.
Publicado: (2021)

Expression, characterization, and site-directed mutagenesis of UDP-glycosyltransferase UGT88A1 from Arabidopsis thaliana
por: Weng, Jingyuan, et al.
Publicado: (2019)

TaUGT6, a Novel UDP-Glycosyltransferase Gene Enhances the Resistance to FHB and DON Accumulation in Wheat
por: He, Yi, et al.
Publicado: (2020)

Genome-wide analysis of UDP-glycosyltransferases family and identification of UGT genes involved in abiotic stress and flavonol biosynthesis in Nicotiana tabacum
por: Yang, Qing, et al.
Publicado: (2023)

Structure-function and engineering of plant UDP-glycosyltransferase
por: Wang, Mengya, et al.
Publicado: (2023)

Editorial: Invertebrate UDP-Glycosyltransferases: Nomenclature, Diversity and Functions
por: Ahn, Seung-Joon, et al.
Publicado: (2021)

Control of sexuality by the sk1-encoded UDP-glycosyltransferase of maize
por: Hayward, Andrew P., et al.
Publicado: (2016)

UDP-Glycosyltransferases and Albendazole Metabolism in the Juvenile Stages of Haemonchus contortus
por: Kellerová, Pavlína, et al.
Publicado: (2020)

UGT88B2: A promiscuous O-glycosyltransferase from Carthamus tinctorius
por: Sui, Song-yang, et al.
Publicado: (2020)

UGT74D1 Is a Novel Auxin Glycosyltransferase from Arabidopsis thaliana
por: Jin, Shang-Hui, et al.
Publicado: (2013)

Inhibitory effects of tanshinones towards the catalytic activity of UDP-glucuronosyltransferases (UGTs)
por: Zhang, Xu-Xin, et al.
Publicado: (2017)

Glutathione S-transferases and UDP-glycosyltransferases Are Involved in Response to Aluminum Stress in Flax
por: Dmitriev, Alexey A., et al.
Publicado: (2016)

Modulation of Sex Pheromone Discrimination by a UDP-Glycosyltransferase in Drosophila melanogaster
por: Fraichard, Stéphane, et al.
Publicado: (2020)

The induction and inhibition of UDP-glycosyltransferases in Haemonchus contortus and their role in the metabolism of albendazole
por: Dimunová, Diana, et al.
Publicado: (2022)

Solvent Engineering for Nonpolar Substrate Glycosylation Catalyzed by the UDP-Glucose-Dependent Glycosyltransferase UGT71E5: Intensification of the Synthesis of 15-Hydroxy Cinmethylin β-d-Glucoside
por: Jung, Jihye, et al.
Publicado: (2023)

The Activity of Members of the UDP-Glucuronosyltransferase Subfamilies UGT1A and UGT2B is Impaired in Patients with Liver Cirrhosis
por: Duthaler, Urs, et al.
Publicado: (2023)

Validation of a metabolite–GWAS network for Populus trichocarpa family 1 UDP-glycosyltransferases
por: Saint-Vincent, Patricia M. B., et al.
Publicado: (2023)

Correction: UGT74D1 Is a Novel Auxin Glycosyltransferase from Arabidopsis thaliana
por: Jin, Shang-Hui, et al.
Publicado: (2013)

Genome-wide characterization, evolution and expression profiling of UDP-glycosyltransferase family in pomelo (Citrus grandis) fruit
por: Wu, Boping, et al.
Publicado: (2020)

Inhibitory Effect of Sauchinone on UDP-Glucuronosyltransferase (UGT) 2B7 Activity
por: You, Byoung Hoon, et al.
Publicado: (2018)

UGT72, a Major Glycosyltransferase Family for Flavonoid and Monolignol Homeostasis in Plants
por: Speeckaert, Nathanaël, et al.
Publicado: (2022)

Comparative Genomic and Transcriptomic Analyses of Family-1 UDP Glycosyltransferase in Prunus Mume
por: Zhang, Zhiyong, et al.
Publicado: (2018)

Identification of candidate UDP-glycosyltransferases involved in protopanaxadiol-type ginsenoside biosynthesis in Panax ginseng
por: Kang, Kyo Bin, et al.
Publicado: (2018)

Genome-Wide Analysis and Profile of UDP-Glycosyltransferases Family in Alfalfa (Medicago sativa L.) under Drought Stress
por: Ao, Bao, et al.
Publicado: (2022)

Demethylzeylasteral Exhibits Strong Inhibition towards UDP-Glucuronosyltransferase (UGT) 1A6 and 2B7
por: Zhao, Jin-Wen, et al.
Publicado: (2012)

Truncated UDP-glucuronosyltransferase (UGT) from a Crigler–Najjar syndrome type II patient colocalizes with intact UGT in the endoplasmic reticulum
por: Suzuki, Masahiro, et al.
Publicado: (2014)

UDP-glucosyltransferase PpUGT85A2 controls volatile glycosylation in peach
por: Wu, Boping, et al.
Publicado: (2019)

Identification of UDP-glycosyltransferases involved in the biosynthesis of astringent taste compounds in tea (Camellia sinensis)
por: Cui, Lilan, et al.
Publicado: (2016)

The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis
por: Ahn, Seung-Joon, et al.
Publicado: (2021)

Glutathione Promotes Degradation and Metabolism of Residual Fungicides by Inducing UDP-Glycosyltransferase Genes in Tomato
por: Yu, Gaobo, et al.
Publicado: (2022)

Comparative analysis of involvement of UGT1 and UGT2 splice variants of UDP-galactose transporter in glycosylation of macromolecules in MDCK and CHO cell lines
por: Maszczak-Seneczko, Dorota, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_kbg1f2b47h4ut1b9hfk6etca1v