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Hypofractionated Radiotherapy Upregulates Several Immune Checkpoint Molecules in Head and Neck Squamous Cell Carcinoma Cells Independently of the HPV Status While ICOS-L Is Upregulated Only on HPV-Positive Cells

While the treatment of squamous cell carcinoma of the head and neck (HNSCC) with radiotherapy (RT) is complemented more and more by immunotherapy in clinical trials, little is known about the impact of the human papillomavirus (HPV) status or the applied RT scheme on the immune phenotype of the tumo...

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Detalles Bibliográficos
Autores principales: Wimmer, Sebastian, Deloch, Lisa, Hader, Michael, Derer, Anja, Grottker, Fridolin, Weissmann, Thomas, Hecht, Markus, Gostian, Antoniu-Oreste, Fietkau, Rainer, Frey, Benjamin, Gaipl, Udo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430967/
https://www.ncbi.nlm.nih.gov/pubmed/34502022
http://dx.doi.org/10.3390/ijms22179114