Cargando…

Keratin 8/18 Regulate the Akt Signaling Pathway

Keratin 8 and keratin 18 (K8/K18) are intermediate filament proteins that form the obligate heteropolymers in hepatocytes and protect the liver against toxins. The mechanisms of protection include the regulation of signaling pathway associated with cell survival. Previous studies show K8/K18 binding...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lim, Younglan, Kim, Sujin, Yoon, Han-Na, Ku, Nam-On
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430995/ https://www.ncbi.nlm.nih.gov/pubmed/34502133 http://dx.doi.org/10.3390/ijms22179227

Ejemplares similares

Revealing the Roles of Keratin 8/18-Associated Signaling Proteins Involved in the Development of Hepatocellular Carcinoma
por: Lim, Younglan, et al.
Publicado: (2021)

Predisposition to apoptosis in keratin 8-null liver is related to inactivation of NF-κB and SAPKs but not decreased c-Flip
por: Lee, Jongeun, et al.
Publicado: (2013)

A disease- and phosphorylation-related nonmechanical function for keratin 8
por: Ku, Nam-On, et al.
Publicado: (2006)

Lessons from Keratin 18 Knockout Mice: Formation of Novel Keratin Filaments, Secondary Loss of Keratin 7 and Accumulation of Liver-specific Keratin 8-Positive Aggregates
por: Magin, Thomas M., et al.
Publicado: (1998)

Roles of Keratins in Intestine
por: Mun, Jeongwon, et al.
Publicado: (2022)

High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype()()
por: Golob-Schwarzl, Nicole, et al.
Publicado: (2018)

Oblongifolin C inhibits metastasis by up-regulating keratin 18 and tubulins
por: Wang, Xiaoyu, et al.
Publicado: (2015)

Prevalence of genetic variants of keratins 8 and 18 in patients with drug-induced liver injury
por: Usachov, Valentyn, et al.
Publicado: (2015)

Dynamics of human keratin 18 phosphorylation: polarized distribution of phosphorylated keratins in simple epithelial tissues
Publicado: (1995)

Keratins Turn over by Ubiquitination in a Phosphorylation-Modulated Fashion
por: Ku, Nam-On, et al.
Publicado: (2000)

Time-Course Changes of Serum Keratin Concentrations after Liver Transplantation: Contrasting Results of Keratin-18 and Keratin-19 Fragments
por: Macía, Cristina, et al.
Publicado: (2020)

The KEAP1/NRF2 Signaling Pathway in Keratinization
por: Ishitsuka, Yosuke, et al.
Publicado: (2020)

Understanding the Role of Keratins 8 and 18 in Neoplastic Potential of Breast Cancer Derived Cell Lines
por: Iyer, Sapna V., et al.
Publicado: (2013)

Keratin 18 attenuates estrogen receptor α-mediated signaling by sequestering LRP16 in cytoplasm
por: Meng, Yuanguang, et al.
Publicado: (2009)

Signaling from keratins
por: LeBrasseur, Nicole
Publicado: (2006)

Keratins regulate colonic epithelial cell differentiation through the Notch1 signalling pathway
por: Lähdeniemi, Iris A K, et al.
Publicado: (2017)

Keratin 8/18 Regulation of Cell Stiffness-Extracellular Matrix Interplay through Modulation of Rho-Mediated Actin Cytoskeleton Dynamics
por: Bordeleau, François, et al.
Publicado: (2012)

Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells
por: Trisdale, Sarah K., et al.
Publicado: (2016)

Keratin 8 protection of placental barrier function
por: Jaquemar, Daniel, et al.
Publicado: (2003)

Raf-1 activation disrupts its binding to keratins during cell stress
por: Ku, Nam-On, et al.
Publicado: (2004)

Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway
por: Li, Changcan, et al.
Publicado: (2018)

Keratin 8 expression in head and neck epithelia
por: Matthias, Christoph, et al.
Publicado: (2008)

Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation
por: Snider, Natasha T., et al.
Publicado: (2013)

From Strain Stiffening to Softening—Rheological Characterization of Keratins 8 and 18 Networks Crosslinked via Electron Irradiation
por: Elbalasy, Iman, et al.
Publicado: (2022)

Resistin Activates p65 Pathway and Reduces Glycogen Content through Keratin 8
por: Wen, Fengyun, et al.
Publicado: (2020)

Characterization of In Vivo Keratin 19 Phosphorylation on Tyrosine-391
por: Zhou, Qin, et al.
Publicado: (2010)

Sedimentation Studies of Epidermal Keratins. Keratin A and Keratin B
por: Matoltsy, A. Gedeon
Publicado: (1956)

Honokiol Inhibits Melanoma Growth by Targeting Keratin 18 in vitro and in vivo
por: Liu, Tingting, et al.
Publicado: (2020)

Keratin 8/18 Modulation of Protein Kinase C-mediated Integrin-dependent Adhesion and Migration of Liver Epithelial Cells
por: Bordeleau, François, et al.
Publicado: (2010)

Leukamenin E Induces K8/18 Phosphorylation and Blocks the Assembly of Keratin Filament Networks Through ERK Activation
por: Xia, Bo, et al.
Publicado: (2020)

Externalized Keratin 8: A Target at the Interface of Microenvironment and Intracellular Signaling in Colorectal Cancer Cells
por: Albaret, Marie Alexandra, et al.
Publicado: (2018)

Licochalcone D Inhibits Skin Epidermal Cells Transformation through the Regulation of AKT Signaling Pathways
por: Hwang, Sun-Young, et al.
Publicado: (2023)

Intestinal Cell Barrier Function In Vitro Is Severely Compromised by Keratin 8 and 18 Mutations Identified in Patients with Inflammatory Bowel Disease
por: Zupancic, Tina, et al.
Publicado: (2014)

Keratin 18 phosphorylation as a progression marker of chronic hepatitis B
por: Shi, Ying, et al.
Publicado: (2010)

Keratin 8 overexpression promotes mouse Mallory body formation
por: Nakamichi, Ikuo, et al.
Publicado: (2005)

Keratin 8 Is Required for the Maintenance of Architectural Structure in Thymus Epithelium
por: Odaka, Chikako, et al.
Publicado: (2013)

Increased Phospho-Keratin 8 Isoforms in Colorectal Tumors Associated with EGFR Pathway Activation and Reduced Apoptosis
por: Arentz, Georgia, et al.
Publicado: (2012)

Keratinization of Lung Squamous Cell Carcinoma Is Associated with Poor Clinical Outcome
por: Park, Hye Jung, et al.
Publicado: (2017)

Estrous cycle-dependent changes of Fas expression in the bovine corpus luteum: influence of keratin 8/18 intermediate filaments and cytokines
por: Duncan, Alice, et al.
Publicado: (2012)

Dynamics of keratin assembly: exogenous type I keratin rapidly associates with type II keratin in vivo
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_p6lehfrhorrrjtfqa6jtq0scc6