Cargando…

Sterculic Acid Alters Adhesion Molecules Expression and Extracellular Matrix Compounds to Regulate Migration of Lung Cancer Cells

SIMPLE SUMMARY: Sterculic acid (SA) is a naturally occurring lipid with SCD1 inhibitory activity, but it also modifies many other pathways and underlying gene expression. SCD upregulation has been associated with tumor aggressiveness and progression. Effects of SA treatment over extracellular matrix...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peláez, Rafael, Ochoa, Rodrigo, Pariente, Ana, Villanueva-Martínez, Ángela, Pérez-Sala, Álvaro, Larráyoz, Ignacio M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431022/ https://www.ncbi.nlm.nih.gov/pubmed/34503180 http://dx.doi.org/10.3390/cancers13174370

Ejemplares similares

Genome-Wide Transcriptomic Analysis Identifies Pathways Regulated by Sterculic Acid in Retinal Pigmented Epithelium Cells
por: Pariente, Ana, et al.
Publicado: (2020)

Identification of 7-Ketocholesterol-Modulated Pathways and Sterculic Acid Protective Effect in Retinal Pigmented Epithelium Cells by Using Genome-Wide Transcriptomic Analysis
por: Pariente, Ana, et al.
Publicado: (2023)

Sterculic Acid: The Mechanisms of Action beyond Stearoyl-CoA Desaturase Inhibition and Therapeutic Opportunities in Human Diseases
por: Peláez, Rafael, et al.
Publicado: (2020)

Targeting 7KCh-Induced Cell Death Response Mediated by p38, P2X7 and GSDME in Retinal Pigment Epithelium Cells with Sterculic Acid
por: Pariente, Ana, et al.
Publicado: (2023)

Integrins: Moonlighting Proteins in Invadosome Formation
por: Peláez, Rafael, et al.
Publicado: (2019)

Predictive Biomarkers of Age-Related Macular Degeneration Response to Anti-VEGF Treatment
por: Oca, Ana I., et al.
Publicado: (2021)

Biomarkers as Predictive Factors of Anti-VEGF Response
por: Bobadilla, Miriam, et al.
Publicado: (2022)

Sterculic Acid and Its Analogues Are Potent Inhibitors of Toxoplasma gondii
por: Hao, Pan, et al.
Publicado: (2016)

Clara cell adhesion and migration to extracellular matrix
por: Atkinson, Jeffrey J, et al.
Publicado: (2008)

Cigarette smoke modulates PC3 prostate cancer cell migration by altering adhesion molecules and the extracellular matrix
por: YANG, SUPING, et al.
Publicado: (2015)

High Rate of Mutations of Adhesion Molecules and Extracellular Matrix Glycoproteins in Patients with Adult-Onset Focal and Segmental Glomerulosclerosis
por: Marcos González, Sara, et al.
Publicado: (2023)

Manipulation of body fat composition with sterculic acid can inhibit mammary carcinomas in vivo.
por: Khoo, D. E., et al.
Publicado: (1991)

Extracellular matrix molecules and cell adhesion molecules induce neurites through different mechanisms
Publicado: (1990)

Pretreatment of human retinal pigment epithelial cells with sterculic acid forestalls fenretinide-induced apoptosis
por: William, Samuel, et al.
Publicado: (2022)

The Use of Small-Molecule Compounds for Cell Adhesion and Migration in Regenerative Medicine
por: Mitchell, Juan, et al.
Publicado: (2023)

Human lung tumor-associated antigen identified as an extracellular matrix adhesion molecule
Publicado: (1991)

Cell adhesion to agrin presented as a nanopatterned substrate is consistent with an interaction with the extracellular matrix and not transmembrane adhesion molecules
por: Wolfram, Tobias, et al.
Publicado: (2008)

Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration
por: Wang, William Y., et al.
Publicado: (2018)

Conversion of t11t13 CLA into c9t11 CLA in Caco-2 Cells and Inhibition by Sterculic Oil
por: Schneider, Anne-Catherine, et al.
Publicado: (2012)

Sterculic Oil, a Natural SCD1 Inhibitor, Improves Glucose Tolerance in Obese ob/ob Mice
por: Ortinau, Laura C., et al.
Publicado: (2012)

Determination of Cyclopropenoid Fatty Acids in Ewe Milk Fat by GC-MS after Intravenous Administration of Sterculic Acid
por: Lolli, Veronica, et al.
Publicado: (2020)

Guidebook to the extracellular matrix and adhesion proteins /
Publicado: (1993)

Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness
por: Saladi, Srinivas Vinod, et al.
Publicado: (2010)

The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment
por: Klamer, Sofieke, et al.
Publicado: (2014)

Glycosaminoglycans modulate C6 glioma cell adhesion to extracellular matrix components and alter cell proliferation and cell migration
por: Mendes de Aguiar, Claudia Beatriz Nedel, et al.
Publicado: (2005)

Proteolytic cleavage of transmembrane cell adhesion molecule L1 by extracellular matrix molecule Reelin is important for mouse brain development
por: Lutz, David, et al.
Publicado: (2017)

Evaluation of PC12 Cells’ Proliferation, Adhesion and Migration with the Use of an Extracellular Matrix (CorMatrix) for Application in Neural Tissue Engineering
por: Gębczak, Katarzyna, et al.
Publicado: (2021)

Differential Expression of Extracellular Matrix and Adhesion Molecules in Fetal-Origin Amniotic Epithelial Cells of Preeclamptic Pregnancy
por: Kim, Myung-Sun, et al.
Publicado: (2016)

Gene expression profile of adhesion and extracellular matrix molecules during early stages of skeletal muscle regeneration
por: Ceafalan, Laura C., et al.
Publicado: (2020)

Antagonistic L1 Adhesion Molecule Mimetic Compounds Inhibit Glioblastoma Cell Migration In Vitro
por: Nagaraj, Vini, et al.
Publicado: (2022)

Transchromosomic cell model of Down syndrome shows aberrant migration, adhesion and proteome response to extracellular matrix
por: Delom, Frédéric, et al.
Publicado: (2009)

Extracellular Matrix can Recover the Downregulation of Adhesion Molecules after Cell Detachment and Enhance Endothelial Cell Engraftment
por: He, Ningning, et al.
Publicado: (2015)

The extracellular matrix as an adhesion checkpoint for mammary epithelial function
por: Katz, Elad, et al.
Publicado: (2007)

Molecular Adhesion between Cartilage Extracellular Matrix Macromolecules
por: Rojas, Fredrick P., et al.
Publicado: (2014)

MITF reprograms the extracellular matrix and focal adhesion in melanoma
por: Dilshat, Ramile, et al.
Publicado: (2021)

In mitosis integrins reduce adhesion to extracellular matrix and strengthen adhesion to adjacent cells
por: Huber, Maximilian, et al.
Publicado: (2023)

Extracellular Matrix Molecules Facilitating Vascular Biointegration
por: Wise, Steven G., et al.
Publicado: (2012)

Editorial: Molecules of the extracellular matrix as cancer targets
por: Karamanos, Nikos K., et al.
Publicado: (2022)

Comparison of acute proton, photon, and low-dose priming effects on genes associated with extracellular matrix and adhesion molecules in the lungs
por: Tian, Jian, et al.
Publicado: (2013)

The Roles of Junctional Adhesion Molecules (JAMs) in Cell Migration
por: Wang, Junqi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8c7ovqlhrg7q0s829rp6esmr8v