Increasing Angiogenesis Factors in Hypoxic Diabetic Wound Conditions by siRNA Delivery: Additive Effect of LbL-Gold Nanocarriers and Desloratadine-Induced Lysosomal Escape

Impaired wound healing in people with diabetes has multifactorial causes, with insufficient neovascularization being one of the most important. Hypoxia-inducible factor-1 (HIF-1) plays a central role in the hypoxia-induced response by activating angiogenesis factors. As its activity is under precise...

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Detalles Bibliográficos
Autores principales: Shaabani, Elnaz, Sharifiaghdam, Maryam, Lammens, Joris, De Keersmaecker, Herlinde, Vervaet, Chris, De Beer, Thomas, Motevaseli, Elahe, Ghahremani, Mohammad Hossein, Mansouri, Parvin, De Smedt, Stefaan, Raemdonck, Koen, Faridi-Majidi, Reza, Braeckmans, Kevin, Fraire, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431033/
https://www.ncbi.nlm.nih.gov/pubmed/34502144
http://dx.doi.org/10.3390/ijms22179216

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