Cargando…

Landscape of Biomarkers and Actionable Gene Alterations in Adenocarcinoma of GEJ and Stomach—A Real World Data Analysis

SIMPLE SUMMARY: Molecular tumor signatures are becoming increasingly important in the treatment of metastatic adenocarcinomas of the gastroesophageal junction (GEJ) and stomach (GC). There are few studies available analyzing data from the Caucasian population regarding molecular signatures and bioma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hempel, Louisa, de Oliveira, Julia Veloso, Gaumann, Andreas, Milani, Valeria, Schweneker, Katrin, Schenck, Kristina, Fleischmann, Bastian, Philipp, Patrick, Mederle, Stefanie, Garg, Arun, Piehler, Armin, Gandorfer, Beate, Schick, Cordula, Kleespies, Axel, Sellmann, Ludger, Bartels, Marius, Goetze, Thorsten Oliver, Stein, Alexander, Goekkurt, Eray, Pfitzner, Lucia, Robert, Sebastian, Hempel, Dirk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431038/ https://www.ncbi.nlm.nih.gov/pubmed/34503263 http://dx.doi.org/10.3390/cancers13174453

Ejemplares similares

Rare SARS-CoV-2 antibody development in cancer patients
por: Hempel, Louisa, et al.
Publicado: (2021)

SARS‐CoV‐2 infections in cancer outpatients—Most infected patients are asymptomatic carriers without impact on chemotherapy
por: Hempel, Louisa, et al.
Publicado: (2020)

Responses of patients with cancer to mRNA vaccines depend on the time interval between vaccination and last treatment
por: Donhauser, Lara Victoria, et al.
Publicado: (2023)

1680P SARS-CoV-2 infections in outpatients with cancer: Most infected patients are asymptomatic carriers without impact on chemotherapy
por: Hempel, D., et al.
Publicado: (2020)

A phase II study of perioperative pembrolizumab plus mFOLFOX in patients with potentially resectable esophagus, gastroesophageal junction (GEJ), and stomach adenocarcinoma
por: Sun, Weijing, et al.
Publicado: (2023)

Real world data analysis of next generation sequencing and protein expression in metastatic breast cancer patients
por: Hempel, Dirk, et al.
Publicado: (2020)

Coexistence of Primary GEJ Adenocarcinoma and Pedunculated Gastric Gastrointestinal Stromal Tumor
por: Alkaaki, Aroub, et al.
Publicado: (2018)

A new promising oncogenic target (p.C382R) for treatment with pemigatinib in patients with cholangiocarcinoma
por: Hempel, Louisa, et al.
Publicado: (2022)

Antitumor Activity of Larotrectinib in Esophageal Carcinoma with NTRK Gene Amplification
por: Hempel, Dirk, et al.
Publicado: (2020)

GEJ cancers: gastric or esophageal tumors? searching for the answer according to molecular identity
por: Barra, Williams Fernandes, et al.
Publicado: (2017)

Therapeutic Implications of Epidermal Growth Factor Receptor (EGFR) in the Treatment of Metastatic Gastric/GEJ Cancer
por: Adashek, Jacob J., et al.
Publicado: (2020)

Biomarker analyses in REGARD gastric/GEJ carcinoma patients treated with VEGFR2-targeted antibody ramucirumab
por: Fuchs, Charles S, et al.
Publicado: (2016)

Esophagectomy or Total Gastrectomy for Siewert 2 Gastroesophageal Junction (GEJ) Adenocarcinoma? A Registry-Based Analysis
por: Kamarajah, Sivesh K., et al.
Publicado: (2021)

Clinical Practice Observation of Trastuzumab in Patients with Human Epidermal Growth Receptor 2‐Positive Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction
por: Al‐Batran, Salah‐Eddin, et al.
Publicado: (2020)

Ramucirumab plus irinotecan / leucovorin / 5-FU versus ramucirumab plus paclitaxel in patients with advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction, who failed one prior line of palliative chemotherapy: the phase II/III RAMIRIS study (AIO-STO-0415)
por: Lorenzen, Sylvie, et al.
Publicado: (2023)

Checkpoint inhibitors in metastatic gastric and GEJ cancer: a multi-institutional retrospective analysis of real-world data in a Western cohort
por: Schlintl, Verena, et al.
Publicado: (2022)

Automated Assessment of Breast Positioning Quality in Screening Mammography
por: Brahim, Mouna, et al.
Publicado: (2022)

Ramucirumab in Combination with Pembrolizumab in Treatment-Naïve Advanced Gastric or GEJ Adenocarcinoma: Safety and Antitumor Activity from the Phase 1a/b JVDF Trial
por: Chau, Ian, et al.
Publicado: (2020)

Application value of overlap guiding tube (OGT) in assisting overlap esophagojejunostomy during laparoscopic total gastrectomy for gastric/gastroesophageal junction (G/GEJ) tumors
por: Xinhua, Chen, et al.
Publicado: (2022)

Phase III Study to Evaluate Efficacy and Safety of Andecaliximab With mFOLFOX6 as First-Line Treatment in Patients With Advanced Gastric or GEJ Adenocarcinoma (GAMMA-1)
por: Shah, Manish A., et al.
Publicado: (2021)

The CARDIA-trial protocol: a multinational, prospective, randomized, clinical trial comparing transthoracic esophagectomy with transhiatal extended gastrectomy in adenocarcinoma of the gastroesophageal junction (GEJ) type II
por: Leers, Jessica M., et al.
Publicado: (2020)

EGFR, FLT1 and Heparanase as Markers Identifying Patients at Risk of Short Survival in Cholangiocarcinoma
por: Hoffmann, Andreas-Claudius, et al.
Publicado: (2013)

Sensor and Video: Two Complementary Approaches for Evaluation of Dairy Cow Behavior after Calving Sensor Attachment
por: Pfeiffer, Johanna, et al.
Publicado: (2021)

Efficacy and Safety of Sintilimab in Combination with Concurrent Chemoradiotherapy for Locally Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (SHARED): Study Protocol of a Prospective, Multi-Center, Single-Arm Phase 2 Trial
por: Wei, Jia, et al.
Publicado: (2022)

Probing Mixed-Genotype Infections II: High Multiplicity in Natural Infections of the Trypanosomatid, Crithidia bombi, in Its Host, Bombus spp
por: Tognazzo, Martina, et al.
Publicado: (2012)

Stomach in Chest and Chest in Stomach
por: Badipatla, Kanthi R., et al.
Publicado: (2016)

A study protocol of a randomized phase II trial of perioperative chemoimmunotherapy verses perioperative chemoimmunotherapy plus preoperative chemoradiation for locally advanced gastric (G) or gastroesophageal junction (GEJ) adenocarcinoma: the NeoRacing study
por: Zhou, Menglong, et al.
Publicado: (2022)

Reply: Is thymidylate synthase a reliable predictor for response and survival during hepatic arterial infusion for hepatic metastasis from colorectal cancer
por: Goekkurt, E, et al.
Publicado: (2006)

Intersection calculus on surfaces with applications to 3-manifolds
por: Hempel, John
Publicado: (1983)

Development of a Novel Diamond Based Detector for Machine Induced Background and Luminosity Measurements
por: Hempel, Maria
Publicado: (2017)

The SUPRENUM communications subroutine library for grid-oriented problems
por: Hempel, R
Publicado: (1987)

Application of Diamond Based Beam Loss Monitors at LHC
por: Hempel, Maria
Publicado: (2013)

3-manifolds
por: Hempel, John
Publicado: (2004)

Ion traps and the road to fault tolerant quantum computing
por: Hempel, Cornelius
Publicado: (2022)

Probiotics for diarrhoea
por: Hempel, Susanne
Publicado: (2014)

Novel Reflections on the Autonomy and Responsibility of Science
por: Hempel, Fabian
Publicado: (2021)

Probing Mixed-Genotype Infections I: Extraction and Cloning of Infections from Hosts of the Trypanosomatid Crithidia bombi
por: Salathé, Rahel, et al.
Publicado: (2012)

Impact of climate change on parasite infection of an important pollinator depends on host genotypes
por: Manlik, Oliver, et al.
Publicado: (2022)

The Stomach
Publicado: (1887)

The Stomach
Publicado: (1858)

Cannot write session to /tmp/vufind_sessions/sess_ieknmhrdq8ijhdboa5qecdm3h8