Conditional Mutation of Hand1 in the Mouse Placenta Disrupts Placental Vascular Development Resulting in Fetal Loss in Both Early and Late Pregnancy

Congenital heart defects (CHD) affect approximately 1% of all live births, and often require complex surgeries at birth. We have previously demonstrated abnormal placental vascularization in human placentas from fetuses diagnosed with CHD. Hand1 has roles in both heart and placental development and...

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Detalles Bibliográficos
Autores principales: Courtney, Jennifer A., Wilson, Rebecca L., Cnota, James, Jones, Helen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431056/
https://www.ncbi.nlm.nih.gov/pubmed/34502440
http://dx.doi.org/10.3390/ijms22179532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431056/
https://www.ncbi.nlm.nih.gov/pubmed/34502440
http://dx.doi.org/10.3390/ijms22179532

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