Anti-Semaphorin 4D Rescues Motor, Cognitive, and Respiratory Phenotypes in a Rett Syndrome Mouse Model

Rett syndrome is a neurodevelopmental disorder caused by mutations of the methyl-CpG binding protein 2 gene. Abnormal physiological functions of glial cells contribute to pathogenesis of Rett syndrome. Semaphorin 4D (SEMA4D) regulates processes central to neuroinflammation and neurodegeneration incl...

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Detalles Bibliográficos
Autores principales: Mao, Yilin, Evans, Elizabeth E., Mishra, Vikas, Balch, Leslie, Eberhardt, Allison, Zauderer, Maurice, Gold, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431088/
https://www.ncbi.nlm.nih.gov/pubmed/34502373
http://dx.doi.org/10.3390/ijms22179465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431088/
https://www.ncbi.nlm.nih.gov/pubmed/34502373
http://dx.doi.org/10.3390/ijms22179465

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