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Anti-Semaphorin 4D Rescues Motor, Cognitive, and Respiratory Phenotypes in a Rett Syndrome Mouse Model

Rett syndrome is a neurodevelopmental disorder caused by mutations of the methyl-CpG binding protein 2 gene. Abnormal physiological functions of glial cells contribute to pathogenesis of Rett syndrome. Semaphorin 4D (SEMA4D) regulates processes central to neuroinflammation and neurodegeneration incl...

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Detalles Bibliográficos
Autores principales:	Mao, Yilin, Evans, Elizabeth E., Mishra, Vikas, Balch, Leslie, Eberhardt, Allison, Zauderer, Maurice, Gold, Wendy A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431088/ https://www.ncbi.nlm.nih.gov/pubmed/34502373 http://dx.doi.org/10.3390/ijms22179465

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