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Role of RNA Motifs in RNA Interaction with Membrane Lipid Rafts: Implications for Therapeutic Applications of Exosomal RNAs

RNA motifs may promote interactions with exosomes (EXO-motifs) and lipid rafts (RAFT-motifs) that are enriched in exosomal membranes. These interactions can promote selective RNA loading into exosomes. We quantified the affinity between RNA aptamers containing various EXO- and RAFT-motifs and membra...

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Detalles Bibliográficos
Autores principales: Mańka, Rafał, Janas, Pawel, Sapoń, Karolina, Janas, Teresa, Janas, Tadeusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431113/
https://www.ncbi.nlm.nih.gov/pubmed/34502324
http://dx.doi.org/10.3390/ijms22179416