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Doxorubicin-Induced Autophagolysosome Formation Is Partly Prevented by Mitochondrial ROS Elimination in DOX-Resistant Breast Cancer Cells

Since its discovery, mitophagy has been viewed as a protective mechanism used by cancer cells to prevent the induction of mitochondrial apoptosis. Most cancer treatments directly or indirectly cause mitochondrial dysfunction in order to trigger signals for cell death. Elimination of these dysfunctio...

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Detalles Bibliográficos
Autores principales: Ahmadpour, Seyedeh Tayebeh, Desquiret-Dumas, Valérie, Yikilmaz, Ulku, Dartier, Julie, Domingo, Isabelle, Wetterwald, Celine, Orre, Charlotte, Gueguen, Naïg, Brisson, Lucie, Mahéo, Karine, Dumas, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431121/
https://www.ncbi.nlm.nih.gov/pubmed/34502189
http://dx.doi.org/10.3390/ijms22179283