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Metal and Metal Oxide Nanoparticle as a Novel Antibiotic Carrier for the Direct Delivery of Antibiotics

In addition to the benefits, increasing the constant need for antibiotics has resulted in the development of antibiotic bacterial resistance over time. Antibiotic tolerance mainly evolves in these bacteria through efflux pumps and biofilms. Leading to its modern and profitable uses, emerging nanotec...

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Autores principales: Kotrange, Harshada, Najda, Agnieszka, Bains, Aarti, Gruszecki, Robert, Chawla, Prince, Tosif, Mansuri M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431128/
https://www.ncbi.nlm.nih.gov/pubmed/34502504
http://dx.doi.org/10.3390/ijms22179596
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author Kotrange, Harshada
Najda, Agnieszka
Bains, Aarti
Gruszecki, Robert
Chawla, Prince
Tosif, Mansuri M.
author_facet Kotrange, Harshada
Najda, Agnieszka
Bains, Aarti
Gruszecki, Robert
Chawla, Prince
Tosif, Mansuri M.
author_sort Kotrange, Harshada
collection PubMed
description In addition to the benefits, increasing the constant need for antibiotics has resulted in the development of antibiotic bacterial resistance over time. Antibiotic tolerance mainly evolves in these bacteria through efflux pumps and biofilms. Leading to its modern and profitable uses, emerging nanotechnology is a significant field of research that is considered as the most important scientific breakthrough in recent years. Metal nanoparticles as nanocarriers are currently attracting a lot of interest from scientists, because of their wide range of applications and higher compatibility with bioactive components. As a consequence of their ability to inhibit the growth of bacteria, nanoparticles have been shown to have significant antibacterial, antifungal, antiviral, and antiparasitic efficacy in the battle against antibiotic resistance in microorganisms. As a result, this study covers bacterial tolerance to antibiotics, the antibacterial properties of various metal nanoparticles, their mechanisms, and the use of various metal and metal oxide nanoparticles as novel antibiotic carriers for direct antibiotic delivery.
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spelling pubmed-84311282021-09-11 Metal and Metal Oxide Nanoparticle as a Novel Antibiotic Carrier for the Direct Delivery of Antibiotics Kotrange, Harshada Najda, Agnieszka Bains, Aarti Gruszecki, Robert Chawla, Prince Tosif, Mansuri M. Int J Mol Sci Review In addition to the benefits, increasing the constant need for antibiotics has resulted in the development of antibiotic bacterial resistance over time. Antibiotic tolerance mainly evolves in these bacteria through efflux pumps and biofilms. Leading to its modern and profitable uses, emerging nanotechnology is a significant field of research that is considered as the most important scientific breakthrough in recent years. Metal nanoparticles as nanocarriers are currently attracting a lot of interest from scientists, because of their wide range of applications and higher compatibility with bioactive components. As a consequence of their ability to inhibit the growth of bacteria, nanoparticles have been shown to have significant antibacterial, antifungal, antiviral, and antiparasitic efficacy in the battle against antibiotic resistance in microorganisms. As a result, this study covers bacterial tolerance to antibiotics, the antibacterial properties of various metal nanoparticles, their mechanisms, and the use of various metal and metal oxide nanoparticles as novel antibiotic carriers for direct antibiotic delivery. MDPI 2021-09-04 /pmc/articles/PMC8431128/ /pubmed/34502504 http://dx.doi.org/10.3390/ijms22179596 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kotrange, Harshada
Najda, Agnieszka
Bains, Aarti
Gruszecki, Robert
Chawla, Prince
Tosif, Mansuri M.
Metal and Metal Oxide Nanoparticle as a Novel Antibiotic Carrier for the Direct Delivery of Antibiotics
title Metal and Metal Oxide Nanoparticle as a Novel Antibiotic Carrier for the Direct Delivery of Antibiotics
title_full Metal and Metal Oxide Nanoparticle as a Novel Antibiotic Carrier for the Direct Delivery of Antibiotics
title_fullStr Metal and Metal Oxide Nanoparticle as a Novel Antibiotic Carrier for the Direct Delivery of Antibiotics
title_full_unstemmed Metal and Metal Oxide Nanoparticle as a Novel Antibiotic Carrier for the Direct Delivery of Antibiotics
title_short Metal and Metal Oxide Nanoparticle as a Novel Antibiotic Carrier for the Direct Delivery of Antibiotics
title_sort metal and metal oxide nanoparticle as a novel antibiotic carrier for the direct delivery of antibiotics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431128/
https://www.ncbi.nlm.nih.gov/pubmed/34502504
http://dx.doi.org/10.3390/ijms22179596
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